Ruiz-Alcocer Javier, Monsálvez-Romín Daniel, García-Lázaro Santiago, Albarrán-Diego César, Hernández-Verdejo José Luis, Madrid-Costa David
Biotechnology Department, Universidad Europea, Madrid, Spain.
Research Group (GIO), Optics Department, University of Valencia, Valencia, Spain.
Clin Exp Optom. 2018 Mar;101(2):188-192. doi: 10.1111/cxo.12622. Epub 2017 Oct 11.
To evaluate the impact on the ocular surface of a daily disposable hydrogel contact lens with high water content compared with two silicone hydrogel daily disposable lenses of lower water content.
The hydrogel lens assessed was made from nesofilcon A and the silicone hydrogel lenses were made of delefilcon A and stenfilcon A. Contact lens thickness was measured to assess material stability during daily wear, and ocular surface parameters such as tear film osmolarity, tear meniscus area and central corneal thickness were also assessed. Optical quality was analysed for all cases by means of wavefront aberrometry.
The nesofilcon A was shown to be the thinnest lens (p < 0.001), while no differences in lens thickness were found between the two silicone hydrogel lenses (p = 0.495). No significant differences were found in tear film osmolarity, tear meniscus area, central corneal thickness or corneal aberrations, either as a function of the lens measured or time of use (p > 0.05).
In spite of having the thinnest lens and the highest water content, the hydrogel does not significantly impact on tear film and corneal swelling after one day of use in first-time wearers.
评估与两种低含水量的硅水凝胶日抛型隐形眼镜相比，高含水量的日抛型水凝胶隐形眼镜对眼表的影响。
所评估的水凝胶镜片由奈索非康A制成，硅水凝胶镜片由地来非康A和司替非康A制成。测量隐形眼镜厚度以评估日常佩戴期间的材料稳定性，还评估了眼表参数，如泪膜渗透压、泪液弯月面面积和中央角膜厚度。通过波前像差仪分析所有病例的光学质量。
奈索非康A被证明是最薄的镜片（p < 0.001），而两种硅水凝胶镜片之间的镜片厚度没有差异（p = 0.495）。无论是作为所测量镜片的函数还是使用时间的函数，在泪膜渗透压、泪液弯月面面积、中央角膜厚度或角膜像差方面均未发现显著差异（p > 0.05）。
尽管水凝胶镜片最薄且含水量最高，但在初次佩戴者使用一天后，它对泪膜和角膜肿胀没有显著影响。
