Lorente-Velázquez Amalia, García-Montero María, Gómez-Sanz Francisco Javier, Rico Del Viejo Laura, Hernández-Verdejo José Luis, Madrid-Costa David
Department of Optometry and Vision, Faculty of Optics and Optometry, Complutense University of Madrid, Madrid 28037, Spain.
Int J Ophthalmol. 2019 Apr 18;12(4):640-646. doi: 10.18240/ijo.2019.04.19. eCollection 2019.
To assess and compare the impact of a daily disposable contact lens (CL) with high water content on the ocular surface and comfort of the presbyopic and non-presbyopic population after one day of use.
Totally 20 presbyopes and 30 non-presbyopes non-contact wearers were fitted with nesofilcon A CLs. CL thickness was measured to assess material stability during daily wear, and ocular surface parameters were also assessed. Optical quality was analyzed for all cases. In addition, CL comfort was rated.
No significant differences were found in CL thickness, tear film osmolarity, average tear break-up time, bulbar redness, central corneal thickness, corneal volume, root-mean-square of higher-order aberrations (RMS of HOAs) and vertical and horizontal coma, either as a function of the group or time of use. A significant decrease in tear meniscus height and first break-up of the tear film was found in the presbyopic group (=0.038; =0.007 respectively). A decrease in spherical aberration coefficient was found after CL insertion (=0.031 monofocal CL; =0.023 low addition multifocal CL; =0.016 high addition multifocal CL). Multifocal CL were thicker than monofocal CL (=0.045). Comparison between groups showed more discomfort in presbyopes than non-presbyopes (=0.003).
This study evidence that the behavior of the daily disposable CL with high water content seems to be stable during the day of use. Ocular parameters measured during wear show that CL behavior is the same for presbyopes and non-presbyopes, being more uncomfortable for presbyopes.
评估并比较日抛型高含水量隐形眼镜（CL）在使用一天后对老视和非老视人群眼表及舒适度的影响。
共20名老视者和30名非老视非隐形眼镜佩戴者佩戴了奈索非康A隐形眼镜。测量隐形眼镜厚度以评估日常佩戴期间的材料稳定性，同时也评估眼表参数。分析所有病例的光学质量。此外，对隐形眼镜的舒适度进行评分。
无论是作为分组还是使用时间的函数，在隐形眼镜厚度、泪膜渗透压、平均泪膜破裂时间、球结膜充血、中央角膜厚度、角膜体积、高阶像差均方根（HOAs的RMS）以及垂直和水平彗差方面均未发现显著差异。在老视组中发现泪河高度显著降低以及泪膜首次破裂（分别为P = 0.038；P = 0.007）。佩戴隐形眼镜后发现球差系数降低（单焦点隐形眼镜P = 0.031；低附加值多焦点隐形眼镜P = 0.023；高附加值多焦点隐形眼镜P = 0.016）。多焦点隐形眼镜比单焦点隐形眼镜厚（P = 0.045）。组间比较显示老视者比非老视者更不适（P = 0.003）。
本研究证明，日抛型高含水量隐形眼镜在使用当天的表现似乎是稳定的。佩戴期间测量的眼部参数表明，老视者和非老视者的隐形眼镜表现相同，但老视者更不舒服。
