Institut Hospital del Mar d'Investigacions Mèdiques (IMIM), Universitat Pompeu Fabra, 08003 Barcelona, Spain.
Novartis Institute for Biomedical Research, Basel, CH-4002, Switzerland.
Nat Rev Drug Discov. 2017 Dec;16(12):811-812. doi: 10.1038/nrd.2017.177. Epub 2017 Oct 13.
The sharing of legacy preclinical safety data among pharmaceutical companies and its integration with other information sources offers unprecedented opportunities to improve the early assessment of drug safety. Here, we discuss the experience of the eTOX project, which was established through the Innovative Medicines Initiative to explore this possibility.
制药公司之间遗传临床前安全性数据的共享及其与其他信息源的整合为改进药物安全性的早期评估提供了前所未有的机会。在这里,我们讨论了通过创新药物倡议(Innovative Medicines Initiative)建立的 eTOX 项目的经验,该项目旨在探索这种可能性。