• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

急性早幼粒细胞白血病患者处于分子缓解期时t(1;17)(p11;q21)易位的讨论

The discussion of t(1;17)(p11;q21) translocation in acute promyelocytic leukemia patient on molecular remission.

作者信息

Jia Yannan, Li Chengwen, Zhao Jiawei, Song Yang, Wang Juan, Mi Yingchang

机构信息

State Key Laboratory of Experimental Hematology Department of Clinical Hematology, and Department of Hematopathology Institute of Hematology and Blood Diseases Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Tianjin China.

Department of Clinical Hematology Cangzhou Central Hospital Hebei China.

出版信息

Clin Case Rep. 2017 Aug 17;5(10):1594-1596. doi: 10.1002/ccr3.1108. eCollection 2017 Oct.

DOI:10.1002/ccr3.1108
PMID:29026552
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5628225/
Abstract

Some chromosomal aberrations emerging in the course of treatment are probably not related to disease progression, but attribute to the germline alteration. Therefore, the dynamic genetic tests should be performed during the whole treatment process, which is significantly essential for efficacy evaluation and treatment decision- making.

摘要

治疗过程中出现的一些染色体畸变可能与疾病进展无关，而是归因于种系改变。因此，应在整个治疗过程中进行动态基因检测，这对疗效评估和治疗决策至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/128f/5628225/8b03a29a33bc/CCR3-5-1594-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/128f/5628225/8b03a29a33bc/CCR3-5-1594-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/128f/5628225/8b03a29a33bc/CCR3-5-1594-g001.jpg

相似文献

1
The discussion of t(1;17)(p11;q21) translocation in acute promyelocytic leukemia patient on molecular remission.急性早幼粒细胞白血病患者处于分子缓解期时t(1;17)(p11;q21)易位的讨论
Clin Case Rep. 2017 Aug 17;5(10):1594-1596. doi: 10.1002/ccr3.1108. eCollection 2017 Oct.
2
One acute promyelocytic leukemia patient underwent complete molecular remission with consistent presence of t (2; 3) (p25; q21) karyotype.一例急性早幼粒细胞白血病患者在持续存在 t(2;3)(p25;q21)核型的情况下达到完全分子缓解。
Expert Opin Ther Targets. 2013 Oct;17(10):1115-8. doi: 10.1517/14728222.2013.832205. Epub 2013 Aug 30.
3
Acute promyelocytic leukemia with the translocation t(15;17)(q22;q21) associated with t(1;2)(q42~43;q11.2~12): a case report.伴有t(15;17)(q22;q21)易位及t(1;2)(q42~43;q11.2~12)的急性早幼粒细胞白血病：一例报告
J Med Case Rep. 2016 Jul 26;10:203. doi: 10.1186/s13256-016-0982-8.
4
A new chromosome translocation t(7;16)(q31,q22) change during an acute promyelocytic leukemia relapse.一名急性早幼粒细胞白血病复发期间出现新的染色体易位t(7;16)(q31,q22)改变。
Cytogenet Genome Res. 2013;141(1):70-4. doi: 10.1159/000350871. Epub 2013 May 4.
5
Childhood pre-B cell acute lymphoblastic leukemia with translocation t(1;19)(q21.1;p13.3) and two additional chromosomal aberrations involving chromosomes 1, 6, and 13: a case report.伴有t(1;19)(q21.1;p13.3)易位及涉及1号、6号和13号染色体的另外两种染色体畸变的儿童前B细胞急性淋巴细胞白血病：一例报告
J Med Case Rep. 2017 Apr 7;11(1):94. doi: 10.1186/s13256-017-1251-1.
6
A novel clonal t(1;4)(p36.1;q31) translocation in acute promyelocytic leukaemia.急性早幼粒细胞白血病中的一种新型克隆性t(1;4)(p36.1;q31)易位
J Clin Pathol. 2015 May;68(5):391-3. doi: 10.1136/jclinpath-2014-202713. Epub 2015 Mar 10.
7
Acute promyelocytic leukemia: report of a variant translocation, t(1;17).急性早幼粒细胞白血病：1号与17号染色体易位变异型的报告
Cancer Genet Cytogenet. 1986 Feb 1;20(1-2):89-93. doi: 10.1016/0165-4608(86)90110-x.
8
Rearrangements of the retinoic acid receptor alpha and promyelocytic leukemia zinc finger genes resulting from t(11;17)(q23;q21) in a patient with acute promyelocytic leukemia.一名急性早幼粒细胞白血病患者因t(11;17)(q23;q21)导致的维甲酸受体α和早幼粒细胞白血病锌指基因重排。
J Clin Invest. 1993 May;91(5):2260-7. doi: 10.1172/JCI116453.
9
The novel three-way variant t(6;17;15)(p21;q21;q22) in acute promyelocytic leukemia with an FLT3-ITD mutation: A case report.伴有FLT3-ITD突变的急性早幼粒细胞白血病中的新型三向变异t(6;17;15)(p21;q21;q22)：一例报告
Oncol Lett. 2018 Nov;16(5):6121-6125. doi: 10.3892/ol.2018.9413. Epub 2018 Sep 6.
10
Translocation (8;18;16)(p11;q21;p13). A new variant of t(8;16)(p11;p13) in acute monoblastic leukemia: case report and review of the literature.
Cancer Genet Cytogenet. 2006 Feb;165(1):75-8. doi: 10.1016/j.cancergencyto.2005.10.017.

引用本文的文献

1
Spatial-Temporal Genome Regulation in Stress-Response and Cell-Fate Change.应激反应和细胞命运转变中的时空基因组调控。
Int J Mol Sci. 2023 Jan 31;24(3):2658. doi: 10.3390/ijms24032658.

本文引用的文献

1
Acute Promyelocytic Leukemia: A Review and Discussion of Variant Translocations.急性早幼粒细胞白血病：变异易位的综述与讨论
Arch Pathol Lab Med. 2015 Oct;139(10):1308-13. doi: 10.5858/arpa.2013-0345-RS.
2
TBLR1 fuses to retinoid acid receptor α in a variant t(3;17)(q26;q21) translocation of acute promyelocytic leukemia.TBLR1 与维甲酸受体 α 在急性早幼粒细胞白血病的变异 t(3;17)(q26;q21)易位中融合。
Blood. 2014 Aug 7;124(6):936-45. doi: 10.1182/blood-2013-10-528596. Epub 2014 Apr 29.
3
BCOR as a novel fusion partner of retinoic acid receptor alpha in a t(X;17)(p11;q12) variant of acute promyelocytic leukemia.
BCOR 作为急性早幼粒细胞白血病 t(X;17)(p11;q12)变异型中 retinoic acid receptor alpha 的新型融合伙伴。
Blood. 2010 Nov 18;116(20):4274-83. doi: 10.1182/blood-2010-01-264432. Epub 2010 Aug 31.
4
The seventh pathogenic fusion gene FIP1L1-RARA was isolated from a t(4;17)-positive acute promyelocytic leukemia.第七种致病性融合基因FIP1L1-RARA是从t(4;17)阳性急性早幼粒细胞白血病中分离出来的。
Haematologica. 2008 Sep;93(9):1414-6. doi: 10.3324/haematol.12854. Epub 2008 Jul 4.
5
New highly sensitive fluorescence in situ hybridization method to detect PML/RARA fusion in acute promyelocytic leukemia.用于检测急性早幼粒细胞白血病中PML/RARA融合基因的新型高灵敏度荧光原位杂交方法。
Cancer Genet Cytogenet. 2003 Sep;145(2):144-51. doi: 10.1016/s0165-4608(03)00061-x.
6
Variations on a theme: the alternate translocations in APL.主题变奏：急性早幼粒细胞白血病中的交替易位
Leukemia. 2002 Oct;16(10):1927-32. doi: 10.1038/sj.leu.2402720.
7
Deconstructing a disease: RARalpha, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia.解析一种疾病：维甲酸受体α（RARα）、其融合伙伴及其在急性早幼粒细胞白血病发病机制中的作用。
Blood. 1999 May 15;93(10):3167-215.