急性早幼粒细胞白血病患者处于分子缓解期时t(1;17)(p11;q21)易位的讨论
The discussion of t(1;17)(p11;q21) translocation in acute promyelocytic leukemia patient on molecular remission.
作者信息
Jia Yannan, Li Chengwen, Zhao Jiawei, Song Yang, Wang Juan, Mi Yingchang
机构信息
State Key Laboratory of Experimental Hematology Department of Clinical Hematology, and Department of Hematopathology Institute of Hematology and Blood Diseases Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Tianjin China.
Department of Clinical Hematology Cangzhou Central Hospital Hebei China.
出版信息
Clin Case Rep. 2017 Aug 17;5(10):1594-1596. doi: 10.1002/ccr3.1108. eCollection 2017 Oct.
Some chromosomal aberrations emerging in the course of treatment are probably not related to disease progression, but attribute to the germline alteration. Therefore, the dynamic genetic tests should be performed during the whole treatment process, which is significantly essential for efficacy evaluation and treatment decision- making.
治疗过程中出现的一些染色体畸变可能与疾病进展无关，而是归因于种系改变。因此，应在整个治疗过程中进行动态基因检测，这对疗效评估和治疗决策至关重要。
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