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中国老年人心血管疾病的一级预防

Primary prevention of cardiovascular disease in older adults in China.

作者信息

Yong Jian, Lin Dong, Tan Xue-Rui

机构信息

First Affiliated Hospital of Shantou University Medical College, Shantou 515041, Guangdong Province, China.

出版信息

World J Clin Cases. 2017 Sep 16;5(9):349-359. doi: 10.12998/wjcc.v5.i9.349.

Abstract

Over the past two decades, the percentage of Chinese who is 60 years or older has increased from 5.2% in 1995 to 10.5% in 2015. Approximately 16% of the population in China was 60 years old and above in 2015. Since 1990, cardiovascular disease (CVD) has been the leading cause of death in China. Cardiovascular medications of older adults are usually more complicated than younger age groups due to polypharmacy, the presence of comorbidities and more susceptible to treatment-related adverse outcomes. Therefore, effective primary prevention of CVD for older adults is important in sustaining the health of older adults and reducing the burden of the healthcare system. Proper management of CVD-related risk factors, such as hypertension, dyslipidemia, diabetes and obesity, can remarkably reduce risks of CVDs in older Chinese. These risk factors can be modified by managing blood pressure, glucose and lipids lifestyle modifications or receiving medications. Smoking cessation, healthy diets, strict alcohol intake and moderate physical exercise are examples of recommended lifestyle changes for remarkably recovering health conditions of older adults who have hypertension, dyslipidemia, obesity, diabetes or complications. Treatment prescriptions of older adults, in general, are recommended to be individualized and to be initiated at a low dose. The future directions for better primary CVD prevention in older adults include establishing guidelines for primary prevention of CVD for different older adults and further research on better management strategies of CVD risks for elderly Chinese.

摘要

在过去二十年中,中国60岁及以上人口的比例从1995年的5.2%增至2015年的10.5%。2015年,中国约16%的人口年龄在60岁及以上。自1990年以来,心血管疾病(CVD)一直是中国的主要死因。由于多重用药、存在合并症以及更易出现与治疗相关的不良后果,老年人的心血管药物治疗通常比年轻人群更为复杂。因此,对老年人进行有效的心血管疾病一级预防对于维持老年人健康和减轻医疗系统负担至关重要。对高血压、血脂异常、糖尿病和肥胖等心血管疾病相关风险因素进行恰当管理,可显著降低中国老年人患心血管疾病的风险。这些风险因素可通过控制血压、血糖和血脂、改变生活方式或服用药物来加以改善。戒烟、健康饮食、严格控制酒精摄入以及适度体育锻炼是推荐给患有高血压、血脂异常、肥胖、糖尿病或并发症的老年人显著恢复健康状况的生活方式改变示例。一般而言,建议老年人的治疗处方个体化并从小剂量开始。改善老年人心血管疾病一级预防的未来方向包括制定针对不同老年人的心血管疾病一级预防指南,以及进一步研究针对中国老年人更好的心血管疾病风险管理策略。

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