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胰腺癌导致的恶性胃出口梗阻

Malignant Gastric Outlet Obstruction from Pancreatic Cancer.

作者信息

McGrath Clare, Tsang Adrian, Nithianandan Harrish, Nguyen Eric, Bauer Patrick, Dennis Kristopher

机构信息

Faculty of Science, Biomedical Science, University of Ottawa, Ottawa, Ontario, ON, Canada.

Faculty of Medicine, University of Ottawa, Ottawa, Ontario, ON, Canada.

出版信息

Case Rep Gastroenterol. 2017 Sep 6;11(3):511-515. doi: 10.1159/000480070. eCollection 2017 Sep-Dec.

DOI:10.1159/000480070
PMID:29033771
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5637001/
Abstract

Patients with advanced-stage pancreatic cancer are typically burdened by many symptoms that impair functioning and worsen quality of life. We report an exceptional case of a 73-year-old woman with T4N1M0 adenocarcinoma of the uncinate process of the pancreas who developed significant gastric outlet obstruction - an uncommon yet potentially life-threatening complication of disease progression. She developed progressive abdominal pain and emesis, and profound dilatation of her stomach was detected on a radiation therapy simulation CT scan that required urgent decompression. Malignant gastric outlet obstruction must be included in the differential diagnosis when patients with known advanced disease of the pancreas present with obstructive upper gastrointestinal symptoms.

摘要

晚期胰腺癌患者通常会受到多种症状的困扰,这些症状会影响身体机能并降低生活质量。我们报告了一例特殊病例,一名73岁女性,患有胰腺钩突T4N1M0腺癌,出现了严重的胃出口梗阻——这是疾病进展中一种罕见但可能危及生命的并发症。她出现了进行性腹痛和呕吐,在放射治疗模拟CT扫描中发现胃部明显扩张,需要紧急减压。当已知患有晚期胰腺疾病的患者出现梗阻性上消化道症状时,必须将恶性胃出口梗阻纳入鉴别诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/553a/5637001/fdd953980c17/crg-0011-0511-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/553a/5637001/59f3358d522f/crg-0011-0511-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/553a/5637001/fdd953980c17/crg-0011-0511-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/553a/5637001/59f3358d522f/crg-0011-0511-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/553a/5637001/fdd953980c17/crg-0011-0511-g02.jpg

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本文引用的文献

1
Long-term outcome of palliative therapy for gastric outlet obstruction caused by unresectable gastric cancer in patients with good performance status: endoscopic stenting versus surgery.不可切除胃癌所致胃出口梗阻患者中,具有良好表现状态者行姑息性治疗的长期结果:内镜支架置入与手术。
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Stent versus gastrojejunostomy for the palliation of gastric outlet obstruction: a systematic review.支架置入术与胃空肠吻合术治疗胃出口梗阻的姑息治疗:一项系统评价
BMC Gastroenterol. 2007 Jun 8;7:18. doi: 10.1186/1471-230X-7-18.
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可扩张金属支架置入术治疗胃出口梗阻
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