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开发用于太空飞行的肾结石超声综合管理方法。

DEVELOPING COMPLETE ULTRASONIC MANAGEMENT OF KIDNEY STONES FOR SPACEFLIGHT.

作者信息

Simon Julianna C, Dunmire Barbrina, Bailey Michael R, Sorensen Mathew D

机构信息

Center for Industrial and Medical Ultrasound, Applied Physics Laboratory, University of Washington, 1013 NE 40 St., Seattle, WA 98105 USA.

Department of Mechanical Engineering, University of Washington, Stevens Way, Box 352600, Seattle, WA 98195 USA.

出版信息

J Space Saf Eng. 2016 Sep;3(2):50-57. doi: 10.1016/S2468-8967(16)30018-0. Epub 2017 Jan 25.

DOI:10.1016/S2468-8967(16)30018-0
PMID:29034360
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5640155/
Abstract

Bone demineralization, dehydration, and stasis put astronauts at an increased risk of forming kidney stones in space. The incidence of kidney stones and the potential for a mission-critical event are expected to rise as expeditions become longer and immediate transport to Earth becomes more problematic. At the University of Washington, we are developing an ultrasound-based stone management system to detect stones with S-mode ultrasound imaging, break stones with burst wave lithotripsy (BWL), and reposition stones with ultrasonic propulsion (UP) on Earth and in space. This review discusses the development and current state of these technologies, as well as integration on the flexible ultrasound system sponsored by NASA and the National Space Biomedical Research Institute.

摘要

骨质脱矿、脱水和尿液潴留使宇航员在太空中形成肾结石的风险增加。随着太空任务时间延长以及返回地球的即时运输变得更加困难,肾结石的发病率和关键任务事件发生的可能性预计将会上升。在华盛顿大学,我们正在开发一种基于超声的结石管理系统,该系统利用S模式超声成像检测结石,通过脉冲波碎石术(BWL)击碎结石,并在地球上和太空中利用超声推进(UP)重新定位结石。本文综述了这些技术的发展和现状,以及由美国国家航空航天局(NASA)和国家空间生物医学研究所资助的柔性超声系统的集成情况。

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本文引用的文献

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Effect of Carbon Dioxide on the Twinkling Artifact in Ultrasound Imaging of Kidney Stones: A Pilot Study.二氧化碳对肾结石超声成像中闪烁伪像的影响:一项初步研究。
Ultrasound Med Biol. 2017 May;43(5):877-883. doi: 10.1016/j.ultrasmedbio.2016.12.010. Epub 2017 Feb 9.
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Stone-Mode Ultrasound for Determining Renal Stone Size.用于确定肾结石大小的结石模式超声检查
J Endourol. 2016 Sep;30(9):958-62. doi: 10.1089/end.2016.0341.
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Urinary Stone Disease: Advancing Knowledge, Patient Care, and Population Health.尿路结石病:推动知识进步、患者护理和人群健康。
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Ultrasonic propulsion of kidney stones.肾结石的超声推进
Curr Opin Urol. 2016 May;26(3):264-70. doi: 10.1097/MOU.0000000000000276.
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First in Human Clinical Trial of Ultrasonic Propulsion of Kidney Stones.肾结石超声推进的首次人体临床试验。
J Urol. 2016 Apr;195(4 Pt 1):956-64. doi: 10.1016/j.juro.2015.10.131. Epub 2015 Oct 30.
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Use of the Acoustic Shadow Width to Determine Kidney Stone Size with Ultrasound.利用声影宽度通过超声确定肾结石大小。
J Urol. 2016 Jan;195(1):171-7. doi: 10.1016/j.juro.2015.05.111. Epub 2015 Aug 22.
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Improved Detection of Kidney Stones Using an Optimized Doppler Imaging Sequence.使用优化的多普勒成像序列改善肾结石的检测
IEEE Int Ultrason Symp. 2014 Sep 3;2014:452-455. doi: 10.1109/ULTSYM.2014.0112.
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Fragmentation of urinary calculi in vitro by burst wave lithotripsy.体外冲击波碎石术对尿路结石的破碎作用
J Urol. 2015 Jan;193(1):338-44. doi: 10.1016/j.juro.2014.08.009. Epub 2014 Aug 9.
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Tools to improve the accuracy of kidney stone sizing with ultrasound.提高超声测量肾结石大小准确性的工具。
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Urology. 2014 Aug;84(2):484-9. doi: 10.1016/j.urology.2014.04.041. Epub 2014 Jun 26.