感染人类的葡萄牙念珠菌对两性霉素B耐药性的产生
Development of resistance to amphotericin B in Candida lusitaniae infecting a human.
作者信息
Pappagianis D, Collins M S, Hector R, Remington J
出版信息
Antimicrob Agents Chemother. 1979 Aug;16(2):123-6. doi: 10.1128/AAC.16.2.123.
Abstract
Candida lusitaniae associated with infection in a patient with acute myelogenous leukemia developed resistance to amphotericin B during systemic treatment of the patient. The organism, when isolated initially, was inhibited by 0.31 mug of amphotericin B per ml in yeast nitrogen base agar, but when isolated (20 days later) just antemortem and postmortem, required 100 and 50 mug/ml, respectively, for complete inhibition at 48 h.
摘要
在一名急性髓性白血病患者感染过程中分离出的葡萄牙念珠菌，在该患者的全身治疗期间对两性霉素B产生了耐药性。最初分离出的该菌株，在酵母氮源琼脂中每毫升被0.31微克两性霉素B抑制，但在（20天后）临死前和死后分离时，在48小时完全抑制分别需要100微克/毫升和50微克/毫升。
相似文献
1
Development of resistance to amphotericin B in Candida lusitaniae infecting a human.感染人类的葡萄牙念珠菌对两性霉素B耐药性的产生
Antimicrob Agents Chemother. 1979 Aug;16(2):123-6. doi: 10.1128/AAC.16.2.123.
2
[Severe pulmonary candidiasis during acute leukosis treated with amphotericin-B; clinical case].[急性白血病患者应用两性霉素B治疗期间发生的严重肺念珠菌病；临床病例]
G Clin Med. 1968 Mar;49(3):256-73.
3
Amphotericin B: emergency challenge in a neutropenic, asthmatic patient with fungal sepsis.两性霉素B：一名中性粒细胞减少、哮喘且患有真菌败血症患者面临的紧急挑战。
J Allergy Clin Immunol. 1995 Sep;96(3):425-7. doi: 10.1016/s0091-6749(95)70064-1.
4
[Antimycotic prophylaxis with oral amphotericin B in patients with acute myeloid leukemia].
Clin Ter. 1986 Sep 30;118(6):427-31.
5
Bilateral Candida endophthalmitis accompanying Candida lusitaniae bloodstream infection: A case report.伴有葡萄牙念珠菌血流感染的双侧念珠菌性眼内炎：一例报告。
J Infect Chemother. 2018 Feb;24(2):147-149. doi: 10.1016/j.jiac.2017.10.002. Epub 2017 Oct 26.
6
Change in colony morphology of Candida lusitaniae in association with development of amphotericin B resistance.葡萄牙念珠菌菌落形态变化与两性霉素B耐药性的发展
Antimicrob Agents Chemother. 2002 May;46(5):1325-8. doi: 10.1128/AAC.46.5.1325-1328.2002.
7
Clinical microbiological case: chronic disseminated candidiasis unresponsive to treatment.
Clin Microbiol Infect. 2002 Jul;8(7):435-6, 442-4. doi: 10.1046/j.1469-0691.2002.00463.x.
8
Fatal septicemia due to amphotericin B-resistant Candida lusitaniae.由耐两性霉素B的葡萄牙念珠菌引起的致死性败血症。
J Clin Microbiol. 1983 Aug;18(2):443-4. doi: 10.1128/jcm.18.2.443-444.1983.
9
Candida lusitaniae catheter-related sepsis.葡萄牙念珠菌导管相关败血症
Ann Pharmacother. 2001 Dec;35(12):1570-4. doi: 10.1345/aph.1A077.
10
Isolation and characterization of fluconazole- and amphotericin B-resistant Candida albicans from blood of two patients with leukemia.从两名白血病患者血液中分离并鉴定对氟康唑和两性霉素B耐药的白色念珠菌。
Antimicrob Agents Chemother. 1997 Jan;41(1):196-9. doi: 10.1128/AAC.41.1.196.
引用本文的文献
1
Revisiting the History of Candidiasis.重访念珠菌病的历史
Cureus. 2025 Feb 11;17(2):e78878. doi: 10.7759/cureus.78878. eCollection 2025 Feb.
2
Biological and genomic analyses of , a novel potential fungal pathogen closely related to (syn. ) and .对一种与……（同义词……）和……密切相关的新型潜在真菌病原体进行生物学和基因组分析。 （注：原文中“Biological and genomic analyses of ”这里的“of ”后面缺少具体内容）
New Microbes New Infect. 2024 Oct 10;62:101506. doi: 10.1016/j.nmni.2024.101506. eCollection 2024 Dec.
3
Understanding the clinical and environmental drivers of antifungal resistance in the One Health context.在“同一健康”背景下理解抗真菌药物耐药性的临床和环境驱动因素。
Microbiology (Reading). 2024 Oct;170(10). doi: 10.1099/mic.0.001512.
4
Genital-oral transmission of ..的生殖器-口腔传播
Int J STD AIDS. 2025 Feb;36(2):158-160. doi: 10.1177/09564624241296582. Epub 2024 Oct 29.
5
Phenotypical Differences at the Physiological and Clinical Level between Two Genetically Closely Related Strains Isolated from Patients.从患者中分离出的两个基因密切相关菌株在生理和临床水平上的表型差异。
J Fungi (Basel). 2024 Jun 28;10(7):460. doi: 10.3390/jof10070460.
6
Identification of Virulence Factors in Isolates of , and with Low Susceptibility and Resistance to Fluconazole and Amphotericin B.对氟康唑和两性霉素B低敏感性及耐药性的、 及 分离株中致病因子的鉴定
Microorganisms. 2024 Jan 20;12(1):212. doi: 10.3390/microorganisms12010212.
7
Mediator Subunit Med15 Regulates Cell Morphology and Mating in .中介亚基Med15调节……中的细胞形态和交配
J Fungi (Basel). 2023 Mar 8;9(3):333. doi: 10.3390/jof9030333.
8
Overview on the Infections Related to Rare Species.稀有物种相关感染概述
Pathogens. 2022 Aug 24;11(9):963. doi: 10.3390/pathogens11090963.
9
Antifungal Susceptibility Testing: A Primer for Clinicians.抗真菌药敏试验：临床医生入门指南。
Open Forum Infect Dis. 2021 Sep 9;8(11):ofab444. doi: 10.1093/ofid/ofab444. eCollection 2021 Nov.
10
Isolation and Identification of a High-Yield Ethyl Caproate-Producing Yeast From and Optimization of Its Fermentation.一株高产己酸乙酯酵母菌的分离鉴定及其发酵条件优化
Front Microbiol. 2021 May 31;12:663744. doi: 10.3389/fmicb.2021.663744. eCollection 2021.
本文引用的文献
1
Factors influencing experimental candidiasis in mice. I. Alloxan diabetes.影响小鼠实验性念珠菌病的因素。I. 四氧嘧啶糖尿病
Yale J Biol Med. 1962 Aug;35(1):96-112.
2
3
Resistance studies of Candida albicans, with special reference to two patients subjected to prolonged antimycotic treatment.
Odontol Tidskr. 1968 Jun 28;76(3):279-94.
4
Fungal sterols and the mode of action of the polyene antibiotics.真菌甾醇与多烯抗生素的作用方式
Adv Appl Microbiol. 1974;17(0):109-34. doi: 10.1016/s0065-2164(08)70556-2.
5
Resistance to polyene antibiotics and correlated sterol changes in two isolates of Candida tropicalis from a patient with an amphotericin B-resistant funguria.来自一名患有两性霉素B耐药真菌尿症患者的两株热带假丝酵母菌对多烯抗生素的耐药性及相关甾醇变化
J Infect Dis. 1974 Jan;129(1):53-8. doi: 10.1093/infdis/129.1.53.
6
Opportunistic fungal infections in patients with neoplastic diseases.肿瘤疾病患者的机会性真菌感染。
Pathol Annu. 1976;11:255-315.
7
Development of amphotericin B-resistant Candida tropicalis in a patient with defective leukocyte function.一名白细胞功能缺陷患者中耐两性霉素B热带念珠菌的出现。
Am J Med Sci. 1978 Jul-Aug;276(1):77-92.
8
Sterol content and polyene antibiotic resistance in isolates of Candida krusei, Candida parakrusei, and Candida tropicalis.克鲁斯假丝酵母、副克鲁斯假丝酵母和热带假丝酵母分离株中的甾醇含量及对多烯抗生素的耐药性
Can J Microbiol. 1977 Apr;23(4):398-401. doi: 10.1139/m77-058.
9
Identification of Candida lusitaniae as an opportunistic yeast in humans.鉴定葡萄牙念珠菌为人类机会性酵母菌。
J Clin Microbiol. 1979 Aug;10(2):202-5. doi: 10.1128/jcm.10.2.202-205.1979.
10
Inhibition of growth of Coccidioides immitis on Sabouraud medium containing polymyxin B.在含有多粘菌素B的沙氏培养基上对粗球孢子菌生长的抑制作用
J Clin Microbiol. 1975 Mar;1(3):335-6. doi: 10.1128/jcm.1.3.335-336.1975.
Zotero 插件