克鲁斯假丝酵母、副克鲁斯假丝酵母和热带假丝酵母分离株中的甾醇含量及对多烯抗生素的耐药性
Sterol content and polyene antibiotic resistance in isolates of Candida krusei, Candida parakrusei, and Candida tropicalis.
作者信息
Safe L M, Safe S H, Subden R E, Morris D C
出版信息
Can J Microbiol. 1977 Apr;23(4):398-401. doi: 10.1139/m77-058.
DOI:10.1139/m77-058
PMID:301053
Abstract
Three isolates, one from each species of Candida krusei, C. parakrusei, and C. tropicalis, obtained from infected patients, were more tolerant of significantly higher concentrations of polyene antibiotics than the corresponding reference wild types. The resistant strains isolated had the same sterols as their wild-type counterparts but in lower concentrations.
摘要
从感染患者中分离出的三株菌株，分别来自克鲁斯念珠菌、副克鲁斯念珠菌和热带念珠菌，它们对多烯抗生素的耐受浓度显著高于相应的参考野生型。分离出的耐药菌株与野生型菌株具有相同的甾醇，但浓度较低。
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