Davis Kimberly H, Su Jun, González Juan Marcos, Trudeau Jeremiah J, Nelson Lauren M, Hauber Brett, Hollis Kelly A
RTI Health Solutions, 3040 Cornwallis Road, Post Office Box 12194, Research Triangle Park, Durham, NC, 27709-2194, UK.
Boehringer Ingelheim Pharmaceuticals, Inc., 900 Ridgebury Road, AOB 1C180, Ridgefield, CT, 06877, USA.
Health Qual Life Outcomes. 2017 Oct 16;15(1):201. doi: 10.1186/s12955-017-0780-z.
Physicians consider ease of use, satisfaction, and preferences when prescribing an inhaler device. These factors may impact appropriate usage and compliance.
The objectives were to quantify the relative importance of inhaler attributes in patients currently using Combivent Respimat by eliciting preferences for performance and convenience attributes assessed by items in the Patient Satisfaction and Preference Questionnaire (PASAPQ). Using a pharmacy database, 19,964 adults in the United States who filled ≥2 Combivent Respimat prescriptions were identified. Of those, 8150 patients were randomly selected to receive invitation letters. The online cross-sectional survey included the PASAPQ and best-worst scaling (BWS) questions. The PASAPQ measures satisfaction with medication attributes across two domains: performance and convenience. BWS questions asked participants to select the most and least important device attributes. A descriptive statistics analysis of the PASAPQ and a random-parameters logit model of BWS responses were conducted.
The survey was completed by 503 participants. Most were female (57.3%), white (88.5%), and 51-70 years old (67.6%). Approximately 47% reported a chronic obstructive pulmonary disease diagnosis, 21.9% asthma, 8.2% other lung disease, and 23.1% more than one lung disease. PASAPQ scores indicated that the majority were satisfied or very satisfied; up to 20% reported being dissatisfied with Combivent Respimat. The three most important inhaler attributes were Feeling that your medicine gets into your lungs, Inhaler works reliably, and Inhaler makes inhaling your medicine easy. The most important attributes corresponded to six of seven items in the PASAPQ performance domain.
Most participants reported satisfaction with Combivent Respimat. Performance attributes were more important than convenience attributes.
医生在开具吸入器装置处方时会考虑其易用性、满意度和偏好。这些因素可能会影响正确使用和依从性。
目标是通过引发患者对《患者满意度和偏好问卷》（PASAPQ）中所评估的性能和便利性属性的偏好，来量化吸入器属性在当前使用可必特雾化吸入器的患者中的相对重要性。利用药房数据库，在美国确定了19964名开具≥2份可必特雾化吸入器处方的成年人。其中，随机选择了8150名患者接收邀请函。在线横断面调查包括PASAPQ和最佳-最差尺度（BWS）问题。PASAPQ在两个领域衡量对药物属性的满意度：性能和便利性。BWS问题要求参与者选择最重要和最不重要的装置属性。对PASAPQ进行描述性统计分析，并对BWS回答进行随机参数logit模型分析。
503名参与者完成了调查。大多数为女性（57.3%）、白人（88.5%），年龄在51 - 70岁之间（67.6%）。约47%报告患有慢性阻塞性肺疾病，21.9%患有哮喘，8.2%患有其他肺部疾病，23.1%患有不止一种肺部疾病。PASAPQ评分表明，大多数人满意或非常满意；高达20%的人报告对可必特雾化吸入器不满意。三个最重要的吸入器属性是感觉药物进入肺部、吸入器可靠工作以及吸入器使吸入药物容易。最重要的属性对应于PASAPQ性能领域七个项目中的六个。
大多数参与者报告对可必特雾化吸入器满意。性能属性比便利性属性更重要。
