Institute of Physical Chemistry, Polish Academy of Sciences, 44/52 ul. Kasprzaka, 01-224 Warsaw, Poland.
SRM Research Institute, Department of Chemistry, SRM University, Kattankulathur - 603203, Chennai, India.
Analyst. 2017 Nov 6;142(22):4299-4307. doi: 10.1039/c7an01084b.
The demand for electrochemical sensors with high sensitivity and reliability, fast response, and excellent selectivity has stimulated intensive research on developing highly active nanomaterials. In this work, freestanding 3D/CoO thorn-like and wire-like (nanowires) nanostructures are directly grown on a flexible carbon fiber paper (CFP) substrate by a single-step hydrothermal process without using surfactants or templates. The 3D/CoO thorn-like nanostructures show higher electrochemical activity than wire-like because of their high conductivity, large specific surface areas, and mesopores on their surface. The characterization of 3D/CoO nanostructures is performed by using high resolution transmission electron microscopy (HRTEM), field emission scanning electron microscopy (FESEM), X-ray photoelectron spectroscopy (XPS), X-ray diffraction analysis (XRD), and electrochemical methods. The 3D/CoO thorn-like nanostructures displayed non-enzymatic higher catalytic activity towards the electrochemical detection of glucose, compared to the 3D/CoO wire-like morphology. The 3D/CoO thorn-like nanostructures show a wide linear range response of glucose concentration ranging from 1 to 1000 μM with a detection limit of 0.046 μM (S/N = 3). The 3D/CoO thorn-like nanostructure-modified CFP electrode selectively detects glucose in the presence of 100-fold excess of interfering compounds. The 3D/CoO thorn-like nanostructure-modified CFP electrode is tested with human blood serum samples and validated with commercial glucose sensors. The newly developed sensor material shows potential for glucose monitoring in clinical and food samples.
具有高灵敏度和可靠性、快速响应和优异选择性的电化学传感器的需求刺激了对开发高活性纳米材料的深入研究。在这项工作中，通过一步水热法，在没有使用表面活性剂或模板的情况下，将独立的 3D/CoO 刺状和线状（纳米线）纳米结构直接生长在柔性碳纤维纸（CFP）基底上。3D/CoO 刺状纳米结构由于其高导电性、大比表面积和表面上的中孔，表现出比线状更高的电化学活性。通过高分辨率透射电子显微镜（HRTEM）、场发射扫描电子显微镜（FESEM）、X 射线光电子能谱（XPS）、X 射线衍射分析（XRD）和电化学方法对 3D/CoO 纳米结构进行了表征。与 3D/CoO 线状形态相比，3D/CoO 刺状纳米结构对葡萄糖的电化学检测表现出非酶促更高的催化活性。3D/CoO 刺状纳米结构对葡萄糖浓度的线性范围响应从 1 到 1000 μM，检测限为 0.046 μM（S/N = 3）。3D/CoO 刺状纳米结构修饰的 CFP 电极在存在 100 倍过量干扰化合物的情况下选择性地检测葡萄糖。3D/CoO 刺状纳米结构修饰的 CFP 电极用人体血清样本进行了测试，并与商业葡萄糖传感器进行了验证。新开发的传感器材料在临床和食品样本中的葡萄糖监测中具有潜力。
