Ma Jingwen, Wang Jun, Wang Min, Zhang Guoliang, Peng Wenchao, Li Yang, Fan Xiaobin, Zhang Fengbao
Lab of Advanced Nano-Structures & Transfer Processes, Department of Chemical Engineering, Tianjin University, Tianjin 300354, China.
Nanomaterials (Basel). 2018 Jan 29;8(2):73. doi: 10.3390/nano8020073.
Mass transfer plays a significant role in a sensor's performance, because the substrate can be detected only when it contacts with the active catalytic surface. In this work, cuprous oxide mesoporous nanospheres (Cu₂O MPNS) with different pore size distributions are fabricated and applied as electrocatalysts for glucose detection. The small pore Cu₂O (SP-Cu₂O, mean pore size of 5.3 nm) and large pore Cu₂O (LP-Cu₂O, mean pore size of 16.4 nm) spheres are prepared by the template method and an etching treatment. The obtained two kinds of Cu₂O MPNS exhibit high porosity with a similar specific surface area of 61.2 and 63.4 (m²·g), respectively. The prepared Cu₂O MPNS are used to construct an electrochemical non-enzymatic glucose sensor. The results show that the LP-Cu₂O exhibits better performance than SP-Cu₂O, which illustrates that the internal diffusion takes a great impact on the performance of the sensor. The LP-Cu₂O modified electrode possesses a high and reproducible sensitivity of 2116.9 μA mM·cm at the applied potential of 0.6 V with a wide detection range of 0.003-7.8 mM and a low detection limit of 0.42 μM.
传质在传感器性能中起着重要作用，因为只有当底物与活性催化表面接触时才能被检测到。在这项工作中，制备了具有不同孔径分布的氧化亚铜介孔纳米球（Cu₂O MPNS），并将其用作葡萄糖检测的电催化剂。通过模板法和蚀刻处理制备了小孔径Cu₂O（SP-Cu₂O，平均孔径5.3 nm）和大孔径Cu₂O（LP-Cu₂O，平均孔径16.4 nm）球。所获得的两种Cu₂O MPNS均具有高孔隙率，比表面积分别为61.2和63.4（m²·g），较为相似。制备的Cu₂O MPNS用于构建电化学非酶葡萄糖传感器。结果表明，LP-Cu₂O的性能优于SP-Cu₂O，这表明内扩散对传感器性能有很大影响。LP-Cu₂O修饰电极在0.6 V的施加电位下具有2116.9 μA mM·cm的高重现性灵敏度，检测范围宽达0.003 - 7.8 mM，检测限低至0.42 μM。
