Lee Yi-Chieh, Chang Sui-Yuan, Lin Kuan-Yin, Chang Lan-Hsin, Liu Wen-Chun, Wu Cheng-Hsin, Sun Hsin-Yun, Hung Chien-Ching, Chang Shan-Chwen
Department of Internal Medicine, Lotung Poh-Ai Hospital, Medical Lo-Hsu Foundation, I-Lan, Taiwan.
Department of Clinical Laboratory Sciences and Medical Biotechnology, National Taiwan University College of Medicine, Taipei, Taiwan.
BMJ Open. 2017 Oct 16;7(10):e015142. doi: 10.1136/bmjopen-2016-015142.
We aimed to investigate the awareness and willingness towards pre-exposure prophylaxis (PrEP) among individuals seeking voluntary counselling and testing (VCT) for HIV in Taiwan, where PrEP is currently not reimbursed by the insurance.
Between April and October 2016, a questionnaire interview was conducted among VCT clients to inquire about the attitudes towards PrEP against HIV infection. Multivariate logistic regression analysis was performed to identify the associated factors with willingness to initiate PrEP.
During the 6-month period, 1173 VCT clients (99.8%) completed the interviews, with 67.4% being homosexual or bisexual male. While 67.2% of the clients knew of postexposure prophylaxis, 40.2% heard of PrEP. Overall, 546 clients (46.5%) were willing to initiate PrEP and 89.5% of them would choose event-driven PrEP. In multivariate analysis, male gender (OR 1.796; 95% CI 1.165 to 2.768), full-time job (OR 1.354; 95% CI 1.052 to 1.742), one-night stand (OR 1.374; 95% CI 1.043 to 1.810), having casual sex partners within 3 months (OR 1.329; 95% CI 1.031 to 1.714), condomless anal sex (OR 1.405; 95% CI 1.122 to 1.878) and ever having chemsex or attending a drug party in the past 1 year (OR 2.571; 95% CI 1.541 to 4.287), regular screening for HIV infection (OR 1.321; 95% CI 1.021 to 1.711) and knowledge of PrEP (OR 1.504; 95% CI, 1.159 to 1.953) were associated with willingness to initiate PrEP.
Understanding the willingness to initiate PrEP against HIV among the VCT clients in Taiwan, which was associated with male gender, risky sexual behaviours and awareness of PrEP, will help inform the implementation of PrEP programme.
在台湾,暴露前预防(PrEP)目前不在保险报销范围内,我们旨在调查寻求艾滋病病毒自愿咨询检测(VCT)的个体对PrEP的知晓情况和意愿。
2016年4月至10月期间,对VCT服务对象进行问卷调查,询问其对预防艾滋病病毒感染的PrEP的态度。进行多因素逻辑回归分析以确定与开始PrEP意愿相关的因素。
在这6个月期间,1173名VCT服务对象(99.8%)完成了访谈,其中67.4%为男同性恋或双性恋男性。虽然67.2%的服务对象知晓暴露后预防,40.2%听说过PrEP。总体而言,546名服务对象(46.5%)愿意开始PrEP,其中89.5%会选择事件驱动型PrEP。在多因素分析中,男性(比值比[OR]1.796;95%置信区间[CI]1.165至2.768)、全职工作(OR 1.354;95%CI 1.052至1.742)、一夜情(OR 1.374;95%CI 1.043至1.810)、在3个月内有临时性伴侣(OR 1.329;95%CI 1.031至1.714)、无保护肛交(OR 1.405;95%CI 1.122至1.878)以及在过去1年中有过化学性行为或参加过吸毒派对(OR 2.571;95%CI 1.541至4.287)、定期进行艾滋病病毒感染筛查(OR 1.321;95%CI 1.021至1.711)和对PrEP的了解(OR 1.504;95%CI 1.159至1.953)与开始PrEP意愿相关。
了解台湾VCT服务对象中开始PrEP预防艾滋病病毒感染的意愿,其与男性、危险的性行为及对PrEP的知晓情况相关,将有助于为PrEP项目的实施提供参考。