Key Laboratory of Animal Epidemiology of the Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing 100193, People's Republic of China.
Beijing Center for Animal Disease Control and Prevention, Beijing 102629, People's Republic of China.
Poult Sci. 2017 Sep 1;96(11):3893-3895. doi: 10.3382/ps/pex209.
Reticuloendotheliosis virus (REV) causes an immunosuppressive, oncogenic, and runting syndrome in many avian hosts worldwide. The immunosuppression caused by REV can decrease the antibody levels of vaccines and subsequent increase susceptibility to secondary infections. There are no commercial vaccines or effective drugs to control REV infections at present. To investigate the REV infection status in chickens in China, 25,224 sera from 573 chicken flocks, collected between 2005 and 2015, were measured for REV antibodies using an enzyme-linked immunosorbent assay. The seroprevalence of REV antibodies in the flocks was 56.20% (322/573) and the overall seroprevalence in individual chickens was 13.91% (3,509/25,224). Of the 23 regions sampled, all provinces, except Heilongjiang, produced positive samples. Guangxi had the highest rate, of 57.84%. The virus-positive rate also tended to increase as the chickens aged. Our study indicates that REV infection has been common in China over the past decade.
网状内皮组织增生病病毒（REV）在世界范围内的许多禽类宿主中引起免疫抑制、致癌和生长迟缓综合征。REV 引起的免疫抑制会降低疫苗的抗体水平，并随后增加对继发感染的易感性。目前尚无控制 REV 感染的商业疫苗或有效药物。为了调查中国鸡群中的 REV 感染状况，我们使用酶联免疫吸附试验对 2005 年至 2015 年间采集的 573 个鸡群的 25224 份血清进行了 REV 抗体检测。鸡群的 REV 抗体阳性率为 56.20%（322/573），单个鸡的抗体阳性率为 13.91%（3509/25224）。在采样的 23 个地区中，除黑龙江外，所有省份均检出阳性样本。广西的阳性率最高，为 57.84%。病毒阳性率也随着鸡龄的增长而有上升的趋势。我们的研究表明，在过去十年中，REV 感染在中国已经很普遍。
