College of Food Science and Engineering, Yangzhou University, Yangzhou 225127, Jiangsu, China.
College of Food Science and Engineering, Yangzhou University, Yangzhou 225127, Jiangsu, China.
Int J Biol Macromol. 2018 Feb;107(Pt B):2242-2250. doi: 10.1016/j.ijbiomac.2017.10.097. Epub 2017 Oct 16.
In recent years, several medicinal plants have been demonstrated as valuable resources of naturally occurring polysaccharide-polyphenolic conjugates. For the first time, this article introduces recent advances of polysaccharide-polyphenolic conjugates isolated from different medicinal plants. The isolation, purification, structural characterization and biological activities of polysaccharide-polyphenolic conjugates are introduced in details. In general, polysaccharide-polyphenolic conjugates can be isolated by hot water or alkaline extraction followed by purification through anion exchange chromatography or gel filtration chromatography. The structures of conjugates are usually characterized by chemical composition analysis, UV-vis, Fourier-transform infrared and nuclear magnetic resonance spectroscopy. Moreover, polysaccharide-polyphenolic conjugates exhibit several biological activities including anticoagulant, antioxidant, radioprotective, anti-platelet, antitussive and bronchodilatory effects. Therefore, polysaccharide-polyphenolic conjugates isolated from medicinal plants are certain to have a bright prospect in the field of food and pharmaceutics.
近年来，一些药用植物已被证明是天然多糖-多酚缀合物的有价值的资源。本文首次介绍了从不同药用植物中分离得到的多糖-多酚缀合物的最新进展。详细介绍了多糖-多酚缀合物的分离、纯化、结构特征和生物活性。一般来说，多糖-多酚缀合物可以通过热水或碱性提取，然后通过阴离子交换色谱或凝胶过滤色谱进行纯化来分离。缀合物的结构通常通过化学成分分析、紫外可见光谱、傅里叶变换红外光谱和核磁共振波谱来表征。此外，多糖-多酚缀合物表现出多种生物活性，包括抗凝、抗氧化、辐射防护、抗血小板、止咳和平喘作用。因此，从药用植物中分离得到的多糖-多酚缀合物在食品和制药领域肯定有广阔的前景。
