Antes Sebastian, Stadie Axel, Müller Simon, Linsler Stefan, Breuskin David, Oertel Joachim
Department of Neurosurgery, Saarland University Medical Center and Saarland University Faculty of Medicine, Homburg, Germany.
Department of Neurosurgery, Saarland University Medical Center and Saarland University Faculty of Medicine, Homburg, Germany.
World Neurosurg. 2018 Jan;109:e642-e650. doi: 10.1016/j.wneu.2017.10.044. Epub 2017 Oct 17.
Telemetric intracranial pressure (ICP) monitoring seems to be a promising therapy-supporting option in shunt-treated patients. Benefits become obvious when headaches are unspecific and clinical symptoms cannot be related to possible overdrainage or underdrainage. In this study, we evaluated a new telemetric device to individually adjust shunt valves according to ICP measurements.
Between December 2015 and November 2016, 25 patients with suspected suboptimal shunt valve settings underwent insertion of a telemetric ICP sensor (Sensor Reservoir; Christoph Miethke, Potsdam, Germany). Over a 1-year period, a total of 183 telemetric ICP measurements and 85 shunt valve adjustments were carried out. Retrospective statistic analyses focused on valve adjustments, ICP values, and clinical outcomes.
ICP-guided valve adjustments positively changed the clinical state in 18 out of 25 patients. Clinical improvement over time was associated with significant changes of the valve settings and ICP values. Interestingly, a therapeutically normalized ICP profile was not automatically associated with clinical improvement.
The Sensor Reservoir is an important and valuable tool for shunt-treated patients suffering from drainage-related problems. The possibility to simultaneously recognize and solve shunt problems represents the decisive advantage. Nevertheless, measurements with the Sensor Reservoir did not allow for the determination of default valve settings or universal target ICP values.
对于接受分流治疗的患者,遥测颅内压(ICP)监测似乎是一种很有前景的治疗辅助手段。当头痛症状不具特异性且临床症状无法与可能的引流过度或引流不足相关联时,其益处就会变得明显。在本研究中,我们评估了一种新型遥测设备,该设备可根据ICP测量值对分流阀进行个体化调整。
2015年12月至2016年11月期间,25例疑似分流阀设置欠佳的患者接受了遥测ICP传感器(Sensor Reservoir;德国波茨坦的Christoph Miethke公司)的植入。在1年的时间里,共进行了183次遥测ICP测量和85次分流阀调整。回顾性统计分析聚焦于阀门调整、ICP值和临床结果。
在25例患者中,有18例患者通过ICP引导的阀门调整使临床状态得到了积极改善。随着时间推移,临床改善与阀门设置和ICP值的显著变化相关。有趣的是,治疗上ICP曲线恢复正常并不一定会带来临床改善。
对于因引流相关问题接受分流治疗的患者,Sensor Reservoir是一种重要且有价值的工具。能够同时识别和解决分流问题是其决定性优势。然而,使用Sensor Reservoir进行测量无法确定默认的阀门设置或通用的目标ICP值。