Insausti-Delgado Ainhoa, Lopez-Larraz Eduardo, Bibian Carlos, Nishimura Yukio, Birbaumer Niels, Ramos-Murguialday Ander
Annu Int Conf IEEE Eng Med Biol Soc. 2017 Jul;2017:2518-2521. doi: 10.1109/EMBC.2017.8037369.
Recent studies have shown the feasibility of spinal cord stimulation (SCS) for motor rehabilitation. Currently, there is an increasing interest in developing closed-loop systems employing SCS for lower-limb recovery. These closed-loop systems are based on the use of neurophysiological signals to modulate the stimulation. It is known that electromagnetic stimulation can introduce undesirable noise to the electrophysiological recordings. However, there is little evidence about how electroencephalographic (EEG) or electromyographic (EMG) activities are corrupted when a trans-spinal magnetic stimulation is applied. This paper studies the effects of magnetic SCS in EEG and EMG activity. Furthermore, a median filter is proposed to ameliorate the effects of the artifacts, and to preserve the neural activity. Our results show that SCS can affect both EEG and EMG, and that, while the median filter works well to clean the EEG activity, it did not improve the contaminations of the EMG activity. The obtained results underline the need of cleaning EMG and EEG signals contaminated by SCS, which is essential for optimal closed-loop rehabilitation.
最近的研究表明脊髓刺激（SCS）用于运动康复具有可行性。目前，人们对开发采用SCS进行下肢恢复的闭环系统的兴趣日益浓厚。这些闭环系统基于使用神经生理信号来调节刺激。众所周知，电磁刺激会给电生理记录引入不良噪声。然而，关于施加经脊髓磁刺激时脑电图（EEG）或肌电图（EMG）活动如何受到干扰的证据很少。本文研究了磁SCS对EEG和EMG活动的影响。此外，提出了一种中值滤波器来改善伪迹的影响，并保留神经活动。我们的结果表明，SCS会影响EEG和EMG，并且，虽然中值滤波器在清理EEG活动方面效果良好，但它并未改善EMG活动的污染情况。所得结果强调了清理受SCS污染的EMG和EEG信号的必要性，这对于优化闭环康复至关重要。
