Lu Jun, Wang Daming
Department of Neurosurgery, Beijing Hospital, National Center of Gerontology, Beijing 100730, China.
Chronic Dis Transl Med. 2016 Nov 30;2(3):135-139. doi: 10.1016/j.cdtm.2016.11.005. eCollection 2016 Sep.
Endovascular therapy for ischemic cerebrovascular diseases has developed rapidly in recent years. The latest clinical trials of acute ischemic stroke have shown promising results with the continued advancement of concepts, techniques, and materials. Mechanical thrombectomy is recommended in the treatment of acute ischemic stroke caused by large vessel occlusion of the anterior circulation, according to the guidelines updated in Europe, USA, and China. The long-term therapeutic efficacy of endovascular stenting for carotid artery stenosis has also been proved noninferior to that of carotid endarterectomy. However, the latest clinical trials have shown that the efficacy of stenting for intracranial artery and vertebral artery stenosis is inferior to that of medical treatment alone, which needs urgent attention through further development and studies.
近年来,缺血性脑血管疾病的血管内治疗发展迅速。随着概念、技术和材料的不断进步,急性缺血性卒中的最新临床试验显示出了令人鼓舞的结果。根据欧洲、美国和中国更新的指南,机械取栓术被推荐用于治疗前循环大血管闭塞所致的急性缺血性卒中。血管内支架置入术治疗颈动脉狭窄的长期疗效也已被证明不劣于颈动脉内膜切除术。然而,最新临床试验表明,支架置入术治疗颅内动脉和椎动脉狭窄的疗效低于单纯药物治疗,这需要通过进一步的发展和研究予以紧急关注。