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Comparison of outcome and interventional complication rate in patients with acute stroke treated with mechanical thrombectomy with and without bridging thrombolysis.比较机械取栓治疗急性脑卒中患者与桥接溶栓治疗患者的结局和介入并发症发生率。
J Neurointerv Surg. 2017 Mar;9(3):229-233. doi: 10.1136/neurintsurg-2015-012236. Epub 2016 Feb 22.
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Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials.血管内血栓切除术治疗大动脉闭塞性缺血性卒中的Meta 分析:来自五项随机试验的个体患者数据汇总分析
Lancet. 2016 Apr 23;387(10029):1723-31. doi: 10.1016/S0140-6736(16)00163-X. Epub 2016 Feb 18.
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Long-Term Results of Stenting versus Endarterectomy for Carotid-Artery Stenosis.颈动脉狭窄支架置入术与动脉内膜切除术的长期结果
N Engl J Med. 2016 Mar 17;374(11):1021-31. doi: 10.1056/NEJMoa1505215. Epub 2016 Feb 18.
4
Randomized Trial of Stent versus Surgery for Asymptomatic Carotid Stenosis.无症状性颈动脉狭窄支架治疗与手术治疗随机试验
N Engl J Med. 2016 Mar 17;374(11):1011-20. doi: 10.1056/NEJMoa1515706. Epub 2016 Feb 17.
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Multicenter Prospective Trial of Stent Placement in Patients with Symptomatic High-Grade Intracranial Stenosis.症状性颅内重度狭窄患者支架置入的多中心前瞻性试验
AJNR Am J Neuroradiol. 2016 Jul;37(7):1275-80. doi: 10.3174/ajnr.A4698. Epub 2016 Feb 11.
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Mechanical thrombectomy in acute ischemic stroke: Consensus statement by ESO-Karolinska Stroke Update 2014/2015, supported by ESO, ESMINT, ESNR and EAN.急性缺血性卒中的机械取栓术:欧洲卒中组织-卡罗林斯卡卒中更新2014/2015共识声明,由欧洲卒中组织、欧洲介入和神经血管治疗学会、欧洲神经放射学会和欧洲神经病学学会支持
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Submaximal angioplasty for symptomatic intracranial atherosclerosis: a prospective Phase I study.症状性颅内动脉粥样硬化的次最大血管成形术:一项前瞻性 I 期研究。
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Endovascular Thrombectomy for Acute Ischemic Stroke: A Meta-analysis.急性缺血性脑卒中的血管内血栓切除术:一项荟萃分析。
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2015 American Heart Association/American Stroke Association Focused Update of the 2013 Guidelines for the Early Management of Patients With Acute Ischemic Stroke Regarding Endovascular Treatment: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association.2015年美国心脏协会/美国卒中协会对2013年急性缺血性卒中患者早期管理指南中血管内治疗部分的重点更新:美国心脏协会/美国卒中协会给医疗专业人员的指南
Stroke. 2015 Oct;46(10):3020-35. doi: 10.1161/STR.0000000000000074. Epub 2015 Jun 29.

缺血性脑血管疾病的血管内治疗进展

Advances in endovascular therapy for ischemic cerebrovascular diseases.

作者信息

Lu Jun, Wang Daming

机构信息

Department of Neurosurgery, Beijing Hospital, National Center of Gerontology, Beijing 100730, China.

出版信息

Chronic Dis Transl Med. 2016 Nov 30;2(3):135-139. doi: 10.1016/j.cdtm.2016.11.005. eCollection 2016 Sep.

DOI:10.1016/j.cdtm.2016.11.005
PMID:29063034
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5643760/
Abstract

Endovascular therapy for ischemic cerebrovascular diseases has developed rapidly in recent years. The latest clinical trials of acute ischemic stroke have shown promising results with the continued advancement of concepts, techniques, and materials. Mechanical thrombectomy is recommended in the treatment of acute ischemic stroke caused by large vessel occlusion of the anterior circulation, according to the guidelines updated in Europe, USA, and China. The long-term therapeutic efficacy of endovascular stenting for carotid artery stenosis has also been proved noninferior to that of carotid endarterectomy. However, the latest clinical trials have shown that the efficacy of stenting for intracranial artery and vertebral artery stenosis is inferior to that of medical treatment alone, which needs urgent attention through further development and studies.

摘要

近年来,缺血性脑血管疾病的血管内治疗发展迅速。随着概念、技术和材料的不断进步,急性缺血性卒中的最新临床试验显示出了令人鼓舞的结果。根据欧洲、美国和中国更新的指南,机械取栓术被推荐用于治疗前循环大血管闭塞所致的急性缺血性卒中。血管内支架置入术治疗颈动脉狭窄的长期疗效也已被证明不劣于颈动脉内膜切除术。然而,最新临床试验表明,支架置入术治疗颅内动脉和椎动脉狭窄的疗效低于单纯药物治疗,这需要通过进一步的发展和研究予以紧急关注。