Researcher, Department of Oral and Maxillofacial Surgery and Oral Medicine, Malmo University, Malmö, Sweden.
Associate Professor, Department of Oral and Maxillofacial Surgery and Oral Medicine, Malmo University, Malmö, Sweden.
Implant Dent. 2017 Dec;26(6):815-819. doi: 10.1097/ID.0000000000000672.
Based on the current evidence, the effect of implant macrogeometry has a significant influence on osseointegration. Thus, this study evaluated histomorphometrically and histologically the bone response to acid-etched in comparison to grit-blasted/acid-etched (GB) and machined control (C) surfaced implants possessing identical macrogeometry placed in high-density bone.
Implant surface topography of the 3 different surfaced implants has previously been characterized. The macrogeometry of the implants were conical, and healing chambers were created in the cortical regions. The 3 groups were placed in the external mandibular body of adult male sheep (n = 5). After 6 weeks in vivo, all samples were retrieved for histologic observation and histomorphometry (eg, bone-to-implant contact [BIC] and bone area fraction occupancy [BAFO]).
No statistical difference was observed for BIC and for BAFO, although there was a tendency that the mean values for BAFO was higher for the textured surface groups.
It is suggested that the effect of surface topography is minimal in high-density bone and osseointegration seemed to be macrogeometry dependent.
基于现有证据，种植体宏观几何形状的影响对骨整合有显著影响。因此，本研究通过组织形态计量学和组织学评估了酸蚀表面与喷砂酸蚀（GB）和机械加工对照（C）表面具有相同宏观几何形状的种植体在高密度骨中的骨反应，这些种植体具有相同的宏观几何形状。
先前已经对 3 种不同表面处理种植体的种植体表面形貌进行了特征描述。种植体的宏观几何形状为圆锥形，在皮质区域形成了愈合室。将这 3 组植入物分别放置在成年雄性绵羊的下颌体外部（n = 5）。体内 6 周后，所有样本均用于组织学观察和组织形态计量学（例如，骨-种植体接触[BIC]和骨面积占有率[BAFO]）评估。
BIC 和 BAFO 之间未观察到统计学差异，尽管纹理表面组的 BAFO 平均值较高。
这表明在高密度骨中表面形貌的影响很小，骨整合似乎依赖于宏观几何形状。
