绵羊体内双酸蚀和喷砂/酸蚀种植体的表面特征及体内评估

Surface characterization and in vivo evaluation of dual Acid-etched and grit-blasted/acid-etched implants in sheep.

作者信息

Yoo Daniel, Marin Charles, Freitas Gileade, Tovar Nick, Bonfante Estevam A, Teixeira Hellen S, Janal Malvin N, Coelho Paulo G

机构信息

*PhD Candidate, Department of Biomaterials and Biomimetics, New York University College of Dentistry, New York, NY. †Assistant Professor, Postgraduate Program in Dentistry, UNIGRANRIO University School of Health Sciences, Rio de Janeiro, Brazil. ‡PhD Candidate, Department of Biomaterials and Biomimetics, New York University College of Dentistry, New York, NY. §Adjunct Professor and Director, Material Analysis and Testing Laboratory, Department of Biomaterials and Biomimetics, New York University College of Dentistry, New York, NY. ‖Assistant Professor, Department of Prosthodontics, University of São Paulo-Bauru College of Dentistry, São Paulo, Brazil. ¶Associate Professor, Department of Epidemiology and Health Promotion, New York University College of Dentistry, New York, NY. #Associate Professor, Department of Biomaterials and Biomimetics, New York University College of Dentistry, New York, NY; Director for Research, Department of Periodontology and Implant Dentistry New York University College of Dentistry, New York, NY; Affiliated Faculty, Division of Engineering, New York University Abu Dhabi, Abu Dhabi, United Arab Emirates.

出版信息

Implant Dent. 2015 Jun;24(3):256-62. doi: 10.1097/ID.0000000000000248.

DOI:10.1097/ID.0000000000000248

PMID:25860908

Abstract

PURPOSE

Dual acid-etching is widely used to modify dental implant topography and enhance early bone healing. This study evaluated the histomorphometric, biomechanical, and histological bone response to acid-etched (AA) in comparison with grit-blasted/acid-etched (GB) and machined control (C) implants within sites of relatively low-bone remodeling rates.

MATERIALS AND METHODS

Implant surface topography was evaluated by scanning electron microscopy and optical interferometry (IFM). Six adult male sheep (n = 6) received 72 Ti-6Al-4V implants (n = 24 per surface) in both ilium (n = 12 per bone bilaterally). The implants remained for 3 and 6 weeks in vivo. The histomorphometric parameters bone-implant contact (BIC) and bone area fraction occupancy (BAFO) were evaluated. Biomechanical analysis consisted of torque-to-interface failure.

RESULTS

IFM analysis showed the highest average surface roughness for GB and the highest density of summits and developed surface area percentage (P < 0.01) for AA. No difference was observed in BAFO for all groups in 3 and 6 weeks. Increased BIC and torque resistance were observed for AA implants at both time points after implantation.

CONCLUSIONS

Overall, improved bone-to-implant response was observed for the AA implant surface.

摘要

目的

双重酸蚀广泛用于改变牙种植体表面形貌并促进早期骨愈合。本研究评估了在骨重塑率相对较低的部位，与喷砂/酸蚀（GB）和机械加工对照（C）种植体相比，酸蚀（AA）种植体的组织形态计量学、生物力学和组织学骨反应。

材料与方法

通过扫描电子显微镜和光学干涉测量法（IFM）评估种植体表面形貌。6只成年雄性绵羊（n = 6）在双侧髂骨（每侧骨植入12枚）植入72枚Ti-6Al-4V种植体（每种表面24枚）。种植体在体内留存3周和6周。评估组织形态计量学参数骨-种植体接触（BIC）和骨面积分数占有率（BAFO）。生物力学分析包括界面破坏扭矩。