Peng Chun-Chih, Chang Jui-Hsing, Lin Hsiang-Yu, Cheng Po-Jen, Su Bai-Horng
Department of Medicine, Mackay Medical College, Taipei, Taiwan; Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan; Mackay Medicine, Nursing and Management College, Taipei, Taiwan.
Department of Neonatology, China Medical University Children's Hospital, Taichung, Taiwan; School of Medicine, China Medical University, Taichung, Taiwan.
Pediatr Neonatol. 2018 Jun;59(3):231-237. doi: 10.1016/j.pedneo.2017.09.001. Epub 2017 Sep 19.
Chorioamnionitis is a common cause of preterm birth and may cause adverse neonatal outcomes, including neurodevelopmental sequelae. Chorioamnionitis has been marked to a heterogeneous setting of conditions characterized by infection or inflammation or both, followed by a great variety in clinical practice for mothers and their newborns. Recently, a descriptive term: "intrauterine inflammation or infection or both" abbreviated as "Triple I" has been proposed by a National Institute of Child Health and Human Development expert panel to replace the term chorioamnionitis. It is particularly important to recognize that an isolated maternal fever does not automatically equate to chorioamnionitis. This article will review the current literature on chorioamnionitis, and introduce the concept of Triple I, as well as recommendations for assessment and management of pregnant women and their newborns with a diagnosis of Triple I.
绒毛膜羊膜炎是早产的常见原因，可能导致不良的新生儿结局，包括神经发育后遗症。绒毛膜羊膜炎被认为是一种以感染或炎症或两者兼具为特征的异质性病症，随后在临床实践中，母亲及其新生儿的情况也多种多样。最近，美国国立儿童健康与人类发展研究所的一个专家小组提出了一个描述性术语：“宫内炎症或感染或两者兼具”，简称为“三联征I”，以取代绒毛膜羊膜炎这一术语。特别重要的是要认识到，单纯的母体发热并不自动等同于绒毛膜羊膜炎。本文将回顾关于绒毛膜羊膜炎的当前文献，介绍三联征I的概念，以及对诊断为三联征I的孕妇及其新生儿进行评估和管理的建议。
