一种用于舌下术前用药的新劳拉西泮制剂。
A new lormetazepam galenical formulation for sublingual premedication.
作者信息
Van Boven M J, Scholtes J L, Collard E, Van Obbergh L, Gribomont B F
机构信息
Department of Anesthesiology, Catholic University of Louvain Medical School, Brussels, Belgium.
出版信息
Acta Anaesthesiol Belg. 1988;39(4):233-7.
This study reports a double-blind evaluation of a new formulation of lormetazepam for sublingual administration, given as a premedicant in 48 female patients undergoing minor gynecological procedures. Both patient's and nurse's assessments for anxiety and sedation were recorded at different times. Anxiolysis and sedation were present 30 minutes after administration of the drug as reported by the patient with a peak effect at 45 minutes. Nurses reported significant differences in sedation only, but already present at 30 minutes after premedication. The memory test showed no persistent effect of the benzodiazepine one day after surgery.
本研究报告了对一种新的舌下含服氯美扎酮制剂的双盲评估，该制剂用于48例接受小型妇科手术的女性患者的术前用药。在不同时间记录了患者和护士对焦虑和镇静情况的评估。患者报告称，用药后30分钟出现抗焦虑和镇静作用，45分钟时达到峰值效应。护士报告仅在镇静方面存在显著差异，且在术前用药后30分钟就已出现。记忆测试表明，术后一天苯二氮䓬类药物没有持续影响。
Zotero 插件