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脉冲Nd-YAG激光联合运动对骨质减少或骨质疏松男性骨密度的长期影响:1年随访

Long-Term Effect of Pulsed Nd-YAG Laser Combined with Exercise on Bone Mineral Density in Men with Osteopenia or Osteoporosis: 1 Year of Follow-Up.

作者信息

Alayat Mohamed Salaheldien Mohamed, Abdel-Kafy Ehab Mohamed, Thabet Ali Abdel Monsif, Abdel-Malek Ahmed Salman, Ali Tariq Helmi, Header Eslam A

机构信息

1 Department of Physical Therapy, Faculty of Applied Medical Sciences, Umm Al-Qura University , Makkah, Saudi Arabia .

2 Umm Al-Qura University Medical Center, Umm Al-Qura University , Makkah, Saudi Arabia .

出版信息

Photomed Laser Surg. 2018 Feb;36(2):105-111. doi: 10.1089/pho.2017.4328. Epub 2017 Oct 25.

DOI:10.1089/pho.2017.4328
PMID:29068756
Abstract

BACKGROUND

A pulsed Nd-YAG laser is an effective physiotherapy modality used as a class IV high-intensity laser therapy (HILT).

OBJECTIVE

The aim of this study is to investigate the efficacy of HILT alone or combined with exercise (HILT+EX) on bone mineral density (BMD) after 24 weeks and at 1 year of follow-up in men with osteopenia or osteoporosis.

METHODS

One hundred men with osteopenia or osteoporosis (mean age, 53.78 [2.89] years; weight, 80.56 [7.33] kg; height 175 [5.30] cm) participated in the study. The T-scores were ≤-1.5. Patients were randomly assigned to four groups: HILT+EX (group I), placebo laser plus exercise (PL+EX; group II), HILT alone (HILT; group III), and PL (group IV). HILT was applied to the lower back and hip regions. Aerobic, weight-bearing, flexibility, strengthening, and balance exercises were performed three times per week for 24 weeks. The measured outcomes were BMD of the L-L spine and total hip. Measurements were taken before and after 24 weeks and at 1 year of follow-up.

RESULTS

Lumbar and total hip BMD significantly increased post-treatment in the HILT+EX and PL+EX groups, but insignificantly in the HILT and PL groups. HILT+EX showed a significantly greater effect than PL+EX did on lumbar BMD, with no significant difference in total hip BMD, after 24 weeks and at follow-up.

CONCLUSIONS

Although HILT alone did not effectively increase lumbar and total hip BMD, HILT combined with exercise was more effective than exercise alone at increasing lumbar BMD after 24 weeks of treatment, with effects lasting up to 1 year.

摘要

背景

脉冲Nd-YAG激光是一种有效的物理治疗方式,用作IV类高强度激光疗法(HILT)。

目的

本研究旨在调查在24周及1年随访期时,HILT单独使用或联合运动(HILT+EX)对骨质减少或骨质疏松男性骨密度(BMD)的疗效。

方法

100名骨质减少或骨质疏松男性(平均年龄53.78[2.89]岁;体重80.56[7.33]千克;身高175[5.30]厘米)参与了本研究。T值≤-1.5。患者被随机分为四组:HILT+EX(I组)、安慰剂激光联合运动(PL+EX;II组)、单纯HILT(HILT;III组)和PL(IV组)。HILT应用于下背部和髋部区域。每周进行三次有氧运动、负重运动、柔韧性运动、强化运动和平衡运动,共24周。测量的结果是L-L脊柱和全髋部的BMD。在24周前后以及1年随访时进行测量。

结果

HILT+EX组和PL+EX组治疗后腰椎和全髋部BMD显著增加,而HILT组和PL组则不显著。在24周及随访时,HILT+EX组对腰椎BMD的影响显著大于PL+EX组,全髋部BMD无显著差异。

结论

尽管单纯HILT不能有效增加腰椎和全髋部BMD,但在治疗24周后,HILT联合运动在增加腰椎BMD方面比单纯运动更有效,且效果可持续长达1年。

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