Department of Neurobiology, Weizmann Institute of Science, Rehovot 7610001, Israel.
Department of Neurobiology, Weizmann Institute of Science, Rehovot 7610001, Israel.
Cell Rep. 2017 Oct 24;21(4):919-925. doi: 10.1016/j.celrep.2017.09.094.
Local field potentials (LFPs) are an important measure of brain activity and have been used to address various mechanistic and behavioral questions. We revealed a prominent whisker-evoked LFP signal in the olfactory bulb and investigated its physiology. This signal, dependent on barrel cortex activation and highly correlated with its local activity, represented a pure volume conduction signal that was sourced back to the activity in the ventro-lateral orbitofrontal cortex, located a few millimeters away. Thus, we suggest that special care should be taken when acquiring and interpreting LFP data.
局部场电位 (LFPs) 是大脑活动的重要测量指标，已被用于解决各种机制和行为问题。我们在嗅球中揭示了一种突出的胡须诱发 LFPs 信号，并研究了其生理学。该信号依赖于皮层激活，并与局部活动高度相关，代表了一种源自几毫米外腹外侧眶额皮质的活动的纯容积传导信号。因此，我们建议在获取和解释 LFPs 数据时应特别小心。
