NYIT College of Osteopathic Medicine, Northern Boulevard, Old Westbury, NY 11568, USA.
SGU School of Medicine, St. George's, West Indies, Grenada.
Am J Emerg Med. 2018 Feb;36(2):341.e1-341.e3. doi: 10.1016/j.ajem.2017.10.044. Epub 2017 Oct 16.
Allergic reaction is a common clinical picture in the Emergency Department (ED). Most allergic reactions are from food or drugs. A detailed history is an integral aspect of determining the causative agent of an allergy. Galactose-alpha-1,3-galactose (alpha-gal) allergy is a tick-acquired red meat allergy that causes delayed-onset allergic reaction or anaphylaxis due to molecular mimicry. Alpha-gal allergy may not be widely known as a cause of allergic reactions. Lack of universal awareness of this phenomenon in the ED and Urgent Care setting could lead to misdiagnosis, or delayed diagnosis. Subsequently, lack of proper instruction to avoid red meat could put patients at risk for future attacks with morbidity or mortality. We report three cases of allergic reaction presumed from red meat consumption secondary to alpha-gal allergy.
过敏反应是急诊科（ED）常见的临床症状。大多数过敏反应来自食物或药物。详细的病史是确定过敏原因的一个重要方面。半乳糖-α-1,3-半乳糖（alpha-gal）过敏是一种通过蜱虫传播的红色肉类过敏，由于分子模拟作用会导致迟发性过敏反应或过敏反应。alpha-gal 过敏可能尚未被广泛认为是过敏反应的原因。ED 和紧急护理环境中普遍缺乏对这一现象的认识可能导致误诊或延迟诊断。随后，由于缺乏适当的避免食用红色肉类的指导，患者可能会面临未来因发病而导致的发病率或死亡率的风险。我们报告了三例因 alpha-gal 过敏导致的疑似由红色肉类消费引起的过敏反应病例。
