Moulakaki Aikaterini I, Monsálvez-Romín Daniel, Domínguez-Vicent Alberto, Esteve-Taboada José J, Montés-Micó Robert
Optometry Research Group (GIO), Optics, Optometry and Vision Sciences Department, University of Valencia, C/Dr. Moliner, 50, 46100, Burjassot, Spain.
Int Ophthalmol. 2018 Dec;38(6):2451-2462. doi: 10.1007/s10792-017-0752-7. Epub 2017 Oct 26.
The aim of this pilot study was to evaluate a new semiautomatic procedure to assess in vivo changes in the crystalline lens and ciliary muscle during accommodation.
A total of 14 subjects were divided into two groups, young (aged between 20 and 25 years) and adult (aged between 35 and 40 years), and measured with an anterior segment optical coherence tomography. A semiautomatic procedure was implemented to measure the central lens thickness (CLT), anterior lens radius (ALR) and the ciliary muscle area (CMA) for the unaccommodated eye and for a vergence of - 3.00 D.
The CLT increase for each population group was smaller than 5%, and the dispersion of each group was similar between them. Contrariwise, the reduction in the ALR was about 30% for both groups, although the young one showed the largest variability. The CMA increase was smaller than 30% for both groups, and the dispersion was similar between them. For each metric, differences between both groups were not statistically significant.
The semiautomatic procedure seems to be useful for the in vivo analysis of the accommodative system. Additionally, the results obtained showed that changes in the CLT were much smaller compared to those obtained for the ALR or CMA.
本初步研究的目的是评估一种新的半自动程序，以评估调节过程中晶状体和睫状肌的体内变化。
总共14名受试者被分为两组，年轻组（年龄在20至25岁之间）和成年组（年龄在35至40岁之间），并使用眼前节光学相干断层扫描进行测量。实施了一种半自动程序，以测量未调节眼和-3.00 D聚散度时的晶状体中心厚度（CLT）、晶状体前半径（ALR）和睫状肌面积（CMA）。
每个年龄组的CLT增加均小于5%，且两组之间的离散度相似。相反，两组的ALR减少均约为30%，尽管年轻组的变异性最大。两组的CMA增加均小于30%，且两组之间的离散度相似。对于每个指标，两组之间的差异均无统计学意义。
半自动程序似乎有助于对调节系统进行体内分析。此外，获得的结果表明，与ALR或CMA相比，CLT的变化要小得多。
