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医疗机构中有效实践的实施:群组随机试验的系统评价

Implementation of effective practices in health facilities: a systematic review of cluster randomised trials.

作者信息

Allanson Emma R, Tunçalp Özge, Vogel Joshua P, Khan Dina N, Oladapo Olufemi T, Long Qian, Gülmezoglu Ahmet Metin

机构信息

School of Women's and Infants' Health, Faculty of Medicine, Dentistry and Health Sciences, University of Western Australia, Crawley, Australia.

Department of Reproductive Health and Research, UNDP/UNFPA/UNICEF/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP), World Health Organization, Geneva, Switzerland.

出版信息

BMJ Glob Health. 2017 Jul 20;2(2):e000266. doi: 10.1136/bmjgh-2016-000266. eCollection 2017.

Abstract

BACKGROUND

The capacity for health systems to support the translation of research in to clinical practice may be limited. The cluster randomised controlled trial (cluster RCT) design is often employed in evaluating the effectiveness of implementation of evidence-based practices. We aimed to systematically review available evidence to identify and evaluate the components in the implementation process at the facility level using cluster RCT designs.

METHODS

All cluster RCTs where the healthcare facility was the unit of randomisation, published or written from 1990 to 2014, were assessed. Included studies were analysed for the components of implementation interventions employed in each. Through iterative mapping and analysis, we synthesised a master list of components used and summarised the effects of different combinations of interventions on practices.

RESULTS

Forty-six studies met the inclusion criteria and covered the specialty groups of obstetrics and gynaecology (n=9), paediatrics and neonatology (n=4), intensive care (n=4), internal medicine (n=20), and anaesthetics and surgery (n=3). Six studies included interventions that were delivered across specialties. Nine components of multifaceted implementation interventions were identified: leadership, barrier identification, tailoring to the context, patient involvement, communication, education, supportive supervision, provision of resources, and audit and feedback. The four main components that were most commonly used were education (n=42, 91%), audit and feedback (n=26, 57%), provision of resources (n=23, 50%) and leadership (n=21, 46%).

CONCLUSIONS

Future implementation research should focus on better reporting of multifaceted approaches, incorporating sets of components that facilitate the translation of research into practice, and should employ rigorous monitoring and evaluation.

摘要

背景

卫生系统支持将研究成果转化为临床实践的能力可能有限。整群随机对照试验(cluster RCT)设计常用于评估循证实践实施的有效性。我们旨在系统回顾现有证据,以识别和评估使用整群随机对照试验设计在机构层面实施过程中的组成部分。

方法

评估了所有以医疗机构作为随机分组单位、于1990年至2014年发表或撰写的整群随机对照试验。对纳入研究分析了各自采用的实施干预措施的组成部分。通过反复映射和分析,我们综合了所使用组成部分的主列表,并总结了不同干预组合对实践的影响。

结果

46项研究符合纳入标准,涵盖妇产科(n = 9)、儿科与新生儿科(n = 4)、重症监护(n = 4)、内科(n = 20)以及麻醉与外科(n = 3)等专业组。6项研究纳入了跨专业实施的干预措施。确定了多方面实施干预的9个组成部分:领导力、障碍识别、因地制宜、患者参与、沟通、教育、支持性监督、资源提供以及审核与反馈。最常用的四个主要组成部分是教育(n = 42,91%)、审核与反馈(n = 26,57%)、资源提供(n = 23,50%)和领导力(n = 21,46%)。

结论

未来的实施研究应侧重于更好地报告多方面方法,纳入有助于将研究转化为实践的一系列组成部分,并应进行严格的监测和评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3710/5656132/6d63f5002ef8/bmjgh-2016-000266f01.jpg

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