肯尼亚的食管癌
Esophageal cancer in Kenya.
作者信息
Odera Joab Otieno, Odera Elizabeth, Githang'a Jessie, Walong Edwin Oloo, Li Fang, Xiong Zhaohui, Chen Xiaoxin Luke
机构信息
Cancer Research Program, JLC-BBRI, North Carolina Central University, Durham 27707, NC, USA.
Integrated Biosciences PhD Program, North Carolina Central University, Durham 27707, NC, USA.
出版信息
Am J Dig Dis (Madison). 2017;4(3):23-33. Epub 2017 Jun 30.
Abstract
Kenya belongs to a high incidence region known as Africa's esophageal cancer (EC) corridor. It has one of the highest incidence rates of EC worldwide, but research on EC in Kenya has gone highly unnoticed. EC in Kenya is unique in its high percentage of young cases (< 30 years of age). In this review, we show the current status of EC in the country. We mainly focus on significant risk factors such as alcohol drinking, genetic factors, malnutrition and hot food/drink. Future directions in the study and prevention of EC in Kenya are also discussed.
摘要
肯尼亚属于一个被称为非洲食管癌（EC）走廊的高发病地区。它是全球食管癌发病率最高的地区之一，但肯尼亚关于食管癌的研究却极少受到关注。肯尼亚的食管癌有其独特之处，即年轻病例（<30岁）的比例很高。在这篇综述中，我们展示了该国食管癌的现状。我们主要关注诸如饮酒、遗传因素、营养不良以及热食/热饮等重要风险因素。此外，还讨论了肯尼亚食管癌研究和预防的未来方向。
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本文引用的文献
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2
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World J Gastroenterol. 2016 Sep 7;22(33):7415-30. doi: 10.3748/wjg.v22.i33.7415.
3
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4
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