眨眼增加可能是眼睑痉挛的先兆：一项纵向研究。
INCREASED BLINKING MAY BE A PRECURSOR OF BLEPHAROSPASM: A LONGITUDINAL STUDY.
作者信息
Conte Antonella, Ferrazzano Gina, Defazio Giovanni, Fabbrini Giovanni, Hallett Mark, Berardelli Alfredo
机构信息
Department of Neurology and Psychiatry, Sapienza, University of Rome, Rome, Italy.
IRCCS Neuromed, Pozzilli, IS, Italy.
出版信息
Mov Disord Clin Pract. 2017 Sep-Oct;4(5):733-736. doi: 10.1002/mdc3.12499. Epub 2017 Jun 2.
Abstract
OBJECTIVE
The aim of this five-year longitudinal study was to investigate whether patients with increased blinking develop orbicularis oculi muscle spasms.
METHODS
Eleven patients who initially manifested increased blinking alone were clinically and neurophysiologically re-evaluated five years later.
RESULTS
By the five-year follow-up assessment, nine of the 11 patients had developed orbicularis oculi muscle spasms. The blink reflex recovery cycle became abnormal whereas somatosensory temporal discrimination, already abnormal at the first evaluation, did not significantly change.
CONCLUSIONS
Our longitudinal study demonstrates that increased blinking may precede blepharospasm and that an abnormal blink reflex recovery cycle reflects the development of orbicularis oculi muscle spasms.
摘要
目的
这项为期五年的纵向研究旨在调查眨眼增多的患者是否会出现眼轮匝肌痉挛。
方法
对11名最初仅表现为眨眼增多的患者在五年后进行临床和神经生理学重新评估。
结果
通过五年的随访评估，11名患者中有9名出现了眼轮匝肌痉挛。眨眼反射恢复周期变得异常，而在首次评估时就已异常的体感时间辨别能力没有显著变化。
结论
我们的纵向研究表明，眨眼增多可能先于眼睑痉挛出现，并且异常的眨眼反射恢复周期反映了眼轮匝肌痉挛的发展。
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INCREASED BLINKING MAY BE A PRECURSOR OF BLEPHAROSPASM: A LONGITUDINAL STUDY.眨眼增加可能是眼睑痉挛的先兆：一项纵向研究。
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8
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