糖尿病患者电解质失衡和血脂异常的评估
Evaluation of Electrolytes Imbalance and Dyslipidemia in Diabetic Patients.
作者信息
Hasona Nabil A, Elasbali Abdulbaset
机构信息
Department of Biochemistry, College of Medicine, University of Hail, PO Box 2440 Hail, Saudi Arabia.
Faculty of Science, Chemistry Department, Biochemistry division, Beni-Suef University, Beni-Suef, Egypt.
出版信息
Med Sci (Basel). 2016 Apr 1;4(2):7. doi: 10.3390/medsci4020007.
Electrolytes and Lipids have always played significant roles, and changes in their concentrations gives good indications of disease progression in a number of non-communicable diseases. Diabetes mellitus is the most common metabolic disorder in the community. Diabetics may suffer from electrolyte disorders due to complications of diabetes mellitus and the medication they receive. Serum glucose, electrolytes (Na⁺, K⁺, Cl and Ca), and lipid profiles (total cholesterol, triglyceride, and HDL-c) were determined in 100 diabetics and in non-diabetic subjects. All the diabetic patients had a significant ( < 0.001) increase in glucose, total cholesterol, triglyceride, chloride and calcium levels. There was significant ( < 0.001) decrease in the serum levels of Na⁺ and K⁺ in all diabetics. It was concluded that differences in lipids and electrolytes found in diabetics may have great potential as a diagnostic tool in clinical practice and have a significant effect upon the risk of contracting many diseases.
电解质和脂质一直发挥着重要作用，其浓度变化能很好地指示多种非传染性疾病的病情进展。糖尿病是社区中最常见的代谢紊乱疾病。糖尿病患者可能因糖尿病并发症及其所接受的药物治疗而出现电解质紊乱。对100名糖尿病患者和非糖尿病受试者测定了血清葡萄糖、电解质（钠⁺、钾⁺、氯和钙）以及血脂谱（总胆固醇、甘油三酯和高密度脂蛋白胆固醇）。所有糖尿病患者的葡萄糖、总胆固醇、甘油三酯、氯和钙水平均显著升高（<0.001）。所有糖尿病患者的血清钠⁺和钾⁺水平均显著降低（<0.001）。研究得出结论，糖尿病患者体内脂质和电解质的差异在临床实践中作为诊断工具可能具有巨大潜力，并且对患多种疾病的风险有重大影响。
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