Divisionof Preventive Oncology, National Center for Tumor Diseases, Im Neuenheimer Feld 460, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 581, D-69120 Heidelberg, Germany.
Team of Physiology, Nutrition and Endocrinology, Biology Department, FSTE, BP 509 Boutalamine, Errachidia, Morocco.
Int J Mol Sci. 2017 Oct 30;18(11):2277. doi: 10.3390/ijms18112277.
This review summarizes available data on argan fruit botany, geographical distribution, traditional uses, environmental interest, socioeconomic role, phytochemistry, as well as health beneficial effects and examination of future prospects. In particular, ethnomedical uses of argan fruits are carried out throughout Morocco where it has been used against various diseases. Different classes of bioactive compounds have been characterized including essential oils, fatty acids, triacylglycerols, flavonoids and their newly reported acylglycosyl derivatives, monophenols, phenolic acids, cinnamic acids, saponins, triterpenes, phytosterols, ubiquinone, melatonin, new aminophenols along with vitamin E among other secondary metabolites. The latter have already shown a wide spectrum of in vitro, and ex vivo biologicalactivities including antioxidant, anti-inflammatory, anti-diabetic, antihypertensive, anti-hypercholesterolemia, analgesic, antimicrobial, molluscicidal anti-nociceptive and anticancer potential. Argan flesh (pulp) contains a broad spectrum of polyphenolic compounds which may have utility for incorporation into nutraceuticals and cosmeceuticals relevant to the food, cosmetic and health industries. Further research is recommended, especially on the health beneficial effects of the aminophenols.
本文综述了阿甘果的植物学、地理分布、传统用途、环境利益、社会经济作用、植物化学，以及对健康有益的影响和未来前景的研究现状。特别是，阿甘果在摩洛哥各地被用于治疗各种疾病，具有广泛的传统医学用途。已鉴定出不同类别的生物活性化合物，包括精油、脂肪酸、三酰基甘油、类黄酮及其新报道的酰基糖苷衍生物、单酚、酚酸、肉桂酸、皂苷、三萜、植物甾醇、泛醌、褪黑素、新氨基酚以及维生素 E 等其他次生代谢物。后者已表现出广泛的体外和离体生物活性，包括抗氧化、抗炎、抗糖尿病、降血压、抗高胆固醇血症、镇痛、抗菌、杀螺、抗伤害和抗癌潜力。阿甘果肉（果肉）含有广泛的多酚类化合物，可用于食品、化妆品和健康行业的营养保健品和化妆品。建议进行进一步的研究，特别是对氨基酚的健康有益作用。
