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头颈部恶性肿瘤的神经周围扩散：文献综述及教学医院治疗病例分析

Perineural spread of malignant head and neck tumors: review of the literature and analysis of cases treated at a teaching hospital.

作者信息

Moreira Mauro César Silveira, Dos Santos Antonio Carlos, Cintra Murilo Bicudo

机构信息

MSc, Radiologist at the Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo (HCFMRP-USP), Ribeirão Preto, SP, Brazil.

PhD, Professor, Head of the Center for Imaging Sciences and Medical Physics of the Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo (HCFMRP-USP), Ribeirão Preto, SP, Brazil.

出版信息

Radiol Bras. 2017 Sep-Oct;50(5):323-327. doi: 10.1590/0100-3984.2015.0215.

DOI:10.1590/0100-3984.2015.0215
PMID:29085166
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5656073/
Abstract

Perineural tumor spread refers to the migration of tumor cells along nerve tissues. It worsens the prognosis, increases the recurrence rate, and diminishes 5-year survival by up to 30%. It is an important finding on imaging tests employed in the staging of patients with head and neck cancers, because it cannot be assessed by the surgeon alone. Nevertheless, it is frequently overlooked. In this study, we reviewed the literature regarding the imaging and pathophysiological aspects of this type of dissemination. We also analyzed ten imaging tests, obtained from a teaching hospital in Brazil, in which there were radiological signs of perineural tumor spread.

摘要

神经周围肿瘤扩散是指肿瘤细胞沿神经组织迁移。它会使预后恶化，增加复发率，并使5年生存率降低多达30%。它是头颈癌患者分期所采用的影像学检查中的一项重要发现，因为外科医生无法单独评估它。然而，它却经常被忽视。在本研究中，我们回顾了关于这种扩散类型的影像学和病理生理学方面的文献。我们还分析了从巴西一家教学医院获得的十份影像学检查，其中存在神经周围肿瘤扩散的放射学征象。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb12/5656073/1dcdd7a3c3ca/rb-50-05-0323-g09.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb12/5656073/060ce3ca7da0/rb-50-05-0323-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb12/5656073/7e8c3d07cf8c/rb-50-05-0323-g10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb12/5656073/378f67b2e635/rb-50-05-0323-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb12/5656073/e50958c8e004/rb-50-05-0323-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb12/5656073/8be8cd6bb148/rb-50-05-0323-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb12/5656073/f0b19e09a03f/rb-50-05-0323-g05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb12/5656073/529965f958a2/rb-50-05-0323-g06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb12/5656073/bf5ee486f038/rb-50-05-0323-g07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb12/5656073/d2a328249d1a/rb-50-05-0323-g08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb12/5656073/1dcdd7a3c3ca/rb-50-05-0323-g09.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb12/5656073/060ce3ca7da0/rb-50-05-0323-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb12/5656073/7e8c3d07cf8c/rb-50-05-0323-g10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb12/5656073/378f67b2e635/rb-50-05-0323-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb12/5656073/e50958c8e004/rb-50-05-0323-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb12/5656073/8be8cd6bb148/rb-50-05-0323-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb12/5656073/f0b19e09a03f/rb-50-05-0323-g05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb12/5656073/529965f958a2/rb-50-05-0323-g06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb12/5656073/bf5ee486f038/rb-50-05-0323-g07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb12/5656073/d2a328249d1a/rb-50-05-0323-g08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb12/5656073/1dcdd7a3c3ca/rb-50-05-0323-g09.jpg

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