Barros Edilberto S, Nascimento Dahan C, Prestes Jonato, Nóbrega Otávio T, Córdova Claúdio, Sousa Fernando, Boullosa Daniel A
Physical Education, Catholic University of Brasilia, Brasília, Brazil.
Medical Sciences, University of Brasilia, Brasília, Brazil.
Front Physiol. 2017 Oct 17;8:779. doi: 10.3389/fphys.2017.00779. eCollection 2017.
In order to understand the effect of endurance running on inflammation, it is necessary to quantify the extent to which acute and chronic running affects inflammatory mediators. The aim of this study was to summarize the literature on the effects of endurance running on inflammation mediators. Electronic searches were conducted on PubMED and Science Direct with no limits of date and language of publication. Randomized controlled trials (RCTs) and non-randomized controlled trials (NRCTs) investigating the acute and chronic effects of running on inflammation markers in runners were reviewed by two researchers for eligibility. The modified Downs and Black checklist for the assesssments of the methodological quality of studies was subsequently used. Fifty-one studies were finally included. There were no studies with elite athletes. Only two studies were chronic interventions. Results revealed that acute and chronic endurance running may affect anti- and pro-inflammatory markers but methodological differences between studies do not allow comparisons or generalization of the results. The information provided in this systematic review would help practitioners for better designing further studies while providing reference values for a better understanding of inflammatory responses after different running events. Further longitudinal studies are needed to identify the influence of training load parameters on inflammatory markers in runners of different levels and training background.
为了了解耐力跑对炎症的影响，有必要量化急性和慢性跑步对炎症介质的影响程度。本研究的目的是总结关于耐力跑对炎症介质影响的文献。在PubMED和ScienceDirect上进行了电子检索，对出版日期和语言没有限制。两名研究人员对调查跑步对跑步者炎症标志物的急性和慢性影响的随机对照试验（RCT）和非随机对照试验（NRCT）进行了资格审查。随后使用了经修改的唐斯和布莱克清单来评估研究的方法学质量。最终纳入了51项研究。没有针对精英运动员的研究。只有两项研究是慢性干预。结果显示，急性和慢性耐力跑可能会影响抗炎和促炎标志物，但研究之间的方法学差异不允许对结果进行比较或归纳。本系统评价提供的信息将有助于从业者更好地设计进一步的研究，同时为更好地理解不同跑步事件后的炎症反应提供参考值。需要进一步的纵向研究来确定训练负荷参数对不同水平和训练背景的跑步者炎症标志物的影响。
