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非正统双组分Rcs磷酸化信号转导系统的新见解

New Insights into the Non-orthodox Two Component Rcs Phosphorelay System.

作者信息

Guo Xiao-Peng, Sun Yi-Cheng

机构信息

MOH Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

出版信息

Front Microbiol. 2017 Oct 17;8:2014. doi: 10.3389/fmicb.2017.02014. eCollection 2017.

DOI:10.3389/fmicb.2017.02014
PMID:29089936
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5651002/
Abstract

The Rcs phosphorelay system, a non-orthodox two-component regulatory system, integrates environmental signals, regulates gene expression, and alters the physiological behavior of members of the Enterobacteriaceae family of Gram-negative bacteria. Recent studies of Rcs system focused on protein interactions, functions, and the evolution of Rcs system components and its auxiliary regulatory proteins. Herein we review the latest advances on the Rcs system proteins, and discuss the roles that the Rcs system plays in the environmental adaptation of various Enterobacteriaceae species.

摘要

Rcs磷酰化信号转导系统是一种非典型的双组分调节系统，它整合环境信号、调节基因表达，并改变革兰氏阴性菌肠杆菌科成员的生理行为。最近对Rcs系统的研究集中在蛋白质相互作用、功能以及Rcs系统组分及其辅助调节蛋白的进化方面。在此，我们综述了Rcs系统蛋白的最新进展，并讨论了Rcs系统在各种肠杆菌科物种环境适应中所起的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fd8/5651002/3b622b39be94/fmicb-08-02014-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fd8/5651002/3b622b39be94/fmicb-08-02014-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fd8/5651002/3b622b39be94/fmicb-08-02014-g001.jpg

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