Ólason Magnús, Andrason Rúnar H, Jónsdóttir Inga H, Kristbergsdóttir Hlín, Jensen Mark P
Reykjalundur Rehabilitation Center, Mosfellsbær, Iceland.
School of Health Sciences, University of Iceland, Reykjavík, Iceland.
Int J Behav Med. 2018 Feb;25(1):55-66. doi: 10.1007/s12529-017-9690-z.
Cognitive behavioral therapy (CBT) is known to be effective for treating depression and anxiety in patients with chronic pain, but there is limited research studying the long-term benefits of CBT in this population. The present study evaluated the effects of CBT provided in the context of an interdisciplinary pain management program with a 3-year follow-up.
One hundred fifteen patients with chronic musculoskeletal pain participated in an interdisciplinary pain management program. Eighty of these patients meeting criteria for CBT treatment were randomized to receive or not receive CBT for depression and anxiety in addition to rehabilitation pain management. The remaining 35 patients constituted a second comparison group. Follow-up data were collected 1 and 3 years post-treatment with 19% of the patients dropping out after 1 year and 34% after 3 years. Attrition analysis did not indicate that there was significant attrition bias in the data.
All three groups evidenced improved depression following treatment (p < 0.001). The pre- to post-treatment effect sizes (Cohen's d) for depression in the CBT treatment group was large (ES = 1.36). The CBT treatment group maintained improvements on all measures at a 3-year follow-up, while the comparison groups did not. This was especially evident with respect to depression (pre-treatment to 3 years follow-up ES = 1.35 and between-group ES = 0.57). Before treatment, 36% of all the patients reported that they were able to work. At 3 years post-treatment, 59%, 58%, and 44% of the patients were working who were in the CBT treatment group, the Comparison group, and the Non-CBT group, respectively.
The results indicate that providing CBT for depression and anxiety as part of a rehabilitation pain management program may enhance the long-term benefits of treatment. This finding, if replicated in additional studies, has important clinical and economic implications.
认知行为疗法(CBT)已知对治疗慢性疼痛患者的抑郁和焦虑有效,但研究CBT在此类人群中的长期益处的研究有限。本研究评估了在跨学科疼痛管理项目背景下提供的CBT,并进行了3年的随访。
115名慢性肌肉骨骼疼痛患者参加了一个跨学科疼痛管理项目。其中80名符合CBT治疗标准的患者被随机分配,除了接受康复疼痛管理外,接受或不接受针对抑郁和焦虑的CBT治疗。其余35名患者组成第二个对照组。在治疗后1年和3年收集随访数据,1年后19%的患者退出,3年后34%的患者退出。失访分析表明数据中不存在显著的失访偏差。
所有三组在治疗后抑郁症状均有改善(p < 0.001)。CBT治疗组抑郁症状的治疗前后效应量(科恩d值)较大(ES = 1.36)。CBT治疗组在3年随访时所有指标均保持改善,而对照组则没有。这在抑郁方面尤为明显(治疗前至3年随访ES = 1.35,组间ES = 0.57)。治疗前,所有患者中有36%报告能够工作。治疗后3年,CBT治疗组、对照组和非CBT组分别有59%、58%和44%的患者在工作。
结果表明,将针对抑郁和焦虑的CBT作为康复疼痛管理项目的一部分提供,可能会增强治疗的长期益处。这一发现若能在更多研究中得到重复,将具有重要的临床和经济意义。