Arslan Gözde, Çelik Levent, Çubuk Rahmi, Çelik Levent, Atasoy Mehmet Mahir
Department of Radiology, Maltepe University School of Medicine, İstanbul, Turkey.
Diagn Interv Radiol. 2017 Nov-Dec;23(6):414-419. doi: 10.5152/dir.2017.17048.
We aimed to retrospectively analyze whether background parenchymal enhancement (BPE) on breast magnetic resonance imaging (MRI) correlates with menarche, menopause, reproductive period, menstrual cycle, gravidity-parity, family history of breast cancer, and the Breast Imaging-Reporting and Data System (BI-RADS) category of the patient.
The study included 126 pre- and 78 postmenopausal women who underwent breast MRI in our institute between 2011 and 2016. Patients had filled a questionnaire form before the MRI. Two radiologists blinded to patient history graded the BPEs and the results were compared and analyzed.
The BPE was correlated with patient age and the day of menstrual cycle (P < 0.01 for both). No correlation was found with menarche age, menopause age, total number of reproductive years, and family history of breast cancer. In the moderate BPE group, only 1 out of 35 patients and in the marked BPE group only 1 out of 13 patients were postmenopausal and had BI-RADS scores of 4 and 5, respectively.
Increased symmetrical BPE is mainly due to current hormonal status in the premenopausal women. High-grade BPE, whether symmetrical or not, is rarely seen in postmenopausal women; hence, these patients should be further investigated or closely followed up.
我们旨在回顾性分析乳腺磁共振成像（MRI）中的背景实质强化（BPE）是否与初潮、绝经、生育期、月经周期、妊娠次数、乳腺癌家族史以及患者的乳腺影像报告和数据系统（BI-RADS）分类相关。
该研究纳入了2011年至2016年间在我院接受乳腺MRI检查的126例绝经前和78例绝经后女性。患者在MRI检查前填写了一份问卷。两名对患者病史不知情的放射科医生对BPE进行分级，并对结果进行比较和分析。
BPE与患者年龄和月经周期天数相关（两者P均<0.01）。未发现与初潮年龄、绝经年龄、生育总年数和乳腺癌家族史相关。在中度BPE组中，35例患者中只有1例为绝经后患者，在显著BPE组中，13例患者中只有1例为绝经后患者，其BI-RADS评分分别为4和5。
绝经前女性对称性BPE增加主要归因于当前的激素状态。绝经后女性很少见到高级别BPE，无论是否对称；因此，应对这些患者进行进一步检查或密切随访。
