Ke Mingjing, Zhu Youchao, Zhang Meng, Gumai Hailiqieguli, Zhang Zhenyan, Xu Junjie, Qian Haifeng
College of Environment, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China.
Xinjiang Key Laboratory of Environmental Pollution and Bioremediation, Chinese Academy of Sciences, Urumqi, 830011, People's Republic of China.
Bull Environ Contam Toxicol. 2017 Dec;99(6):713-718. doi: 10.1007/s00128-017-2205-4. Epub 2017 Nov 2.
The widespread application of copper oxide nanoparticles (nCuO) results in ecological risk when nanoparticles enter the environment. This study clarifies the mechanism of nCuO toxicity in Arabidopsis thaliana seedlings via comparison with copper (Cu) ion bioeffects. Under the same culture conditions, Cu ion exposure exerted a stronger inhibitory effect on plant fresh weight and growth and caused stronger oxidative disruption (measured by malondialdehyde, MDA) than nCuO exposure. The Cu ions also showed a stronger induction effect than did nCuO on the activity of antioxidant enzymes and the transcription of antioxidant-related genes. Dissolved Cu ions contributed a minority of the toxicity of nCuO, implying that nCuO itself showed relative strong phytotoxicity. The work presented here will help increase our understanding of the toxicity of metal nanoparticles in plants.
当纳米颗粒进入环境时，氧化铜纳米颗粒（nCuO）的广泛应用会导致生态风险。本研究通过与铜（Cu）离子生物效应进行比较，阐明了nCuO对拟南芥幼苗的毒性机制。在相同培养条件下，与nCuO暴露相比，Cu离子暴露对植物鲜重和生长的抑制作用更强，并且导致更强的氧化破坏（通过丙二醛，MDA测定）。Cu离子对抗氧化酶活性和抗氧化相关基因转录的诱导作用也比nCuO更强。溶解的Cu离子对nCuO毒性的贡献较小，这意味着nCuO本身表现出相对较强的植物毒性。本文的研究将有助于增进我们对金属纳米颗粒在植物中毒性的理解。
