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1
Water permeability changes studied by 17O nuclear magnetic resonance during differentiation of Friend leukemia cells.利用¹⁷O核磁共振研究弗瑞德白血病细胞分化过程中的水渗透性变化。
Proc Natl Acad Sci U S A. 1979 Jul;76(7):3363-6. doi: 10.1073/pnas.76.7.3363.
2
Amiloride inhibits murine erythroleukemia cell differentiation: evidence for a Ca2+ requirement for commitment.氨氯吡咪抑制小鼠红白血病细胞分化：分化起始需要钙离子的证据。
Proc Natl Acad Sci U S A. 1980 Oct;77(10):5948-52. doi: 10.1073/pnas.77.10.5948.
3
Changes in cyclic adenosine 3':5'-monophosphate levels during induction of differentiation in murine erythroleukemia cells.小鼠红白血病细胞分化诱导过程中3':5'-环磷酸腺苷水平的变化
Cancer Res. 1978 Nov;38(11 Pt 1):3779-83.
4
Lengthening of the G1 phase is not strictly correlated with differentiation in Friend erythroleukemia cells.在弗瑞德红白血病细胞中，G1期的延长与分化并不严格相关。
Proc Natl Acad Sci U S A. 1978 Aug;75(8):3813-7. doi: 10.1073/pnas.75.8.3813.
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Phenotypic variants of differentiation-inducible Friend leukemia lines: isolation and correlation between inducibility and virus release.分化诱导性Friend白血病细胞系的表型变异体：诱导性与病毒释放之间的分离及相关性
Bibl Haematol. 1975 Oct(43):37-47. doi: 10.1159/000399092.
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Uptake, efflux, and hydrolysis of aclacinomycin A in Friend leukemia cells.阿克拉霉素A在弗瑞德白血病细胞中的摄取、外排及水解作用
Cancer Res. 1982 May;42(5):1950-4.
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Early transport changes during erythroid differentiation of Friend leukemic cells.弗氏白血病细胞红系分化过程中的早期转运变化
J Cell Physiol. 1978 Mar;94(3):275-85. doi: 10.1002/jcp.1040940305.
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Interferon and Friend leukemia cells in culture.培养中的干扰素与弗瑞德白血病细胞。
Tex Rep Biol Med. 1977;35:420-8.
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Isolation and characterization of a subline of Friend erythroleukemia cells that differentiate in tissue culture in the absence of inducers.在无诱导剂情况下于组织培养中分化的Friend红白血病细胞亚系的分离与鉴定
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10
Dimethyl sulfoxide-induced differentiation of Friend erythroleukemia cells in the absence of cytokinesis.在无胞质分裂情况下二甲基亚砜诱导的弗氏红白血病细胞分化
Cancer Res. 1979 Oct;39(10):4058-63.

本文引用的文献

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Erythrocytic maturation in vitro of murine (Friend) virus-induced leukemic cells.小鼠（弗瑞德）病毒诱导的白血病细胞在体外的红细胞成熟过程。
Natl Cancer Inst Monogr. 1966 Sep;22:505-22.
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Tumor detection by nuclear magnetic resonance.通过核磁共振进行肿瘤检测。
Science. 1971 Mar 19;171(3976):1151-3. doi: 10.1126/science.171.3976.1151.
3
Hemoglobin synthesis in murine virus-induced leukemic cells in vitro: stimulation of erythroid differentiation by dimethyl sulfoxide.体外小鼠病毒诱导白血病细胞中的血红蛋白合成：二甲基亚砜对红系分化的刺激作用
Proc Natl Acad Sci U S A. 1971 Feb;68(2):378-82. doi: 10.1073/pnas.68.2.378.
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Water diffusion permeability of erythrocytes using an NMR technique.使用核磁共振技术测定红细胞的水扩散渗透率。
Biochim Biophys Acta. 1972 Nov 2;288(2):354-61. doi: 10.1016/0005-2736(72)90256-8.
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Human tumors by NMR.通过核磁共振成像研究人类肿瘤。
Physiol Chem Phys. 1973;5(5):381-402.
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Nuclear magnetic resonance studies of several experimental and human malignant tumors.几种实验性和人类恶性肿瘤的核磁共振研究。
Cancer Res. 1973 Sep;33(9):2156-60.
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Recognition of cancer in vivo by nuclear magnetic resonance.通过核磁共振在体内识别癌症。
Science. 1972 Dec 22;178(4067):1288-90. doi: 10.1126/science.178.4067.1288.
8
Pulsed NMR studies of 17O from H2 17O in frog striated muscle.对青蛙横纹肌中H₂¹⁷O的¹⁷O进行的脉冲核磁共振研究。
Biochim Biophys Acta. 1974 Apr 22;343(2):399-408. doi: 10.1016/0304-4165(74)90104-4.
9
Regulation of hemoglobin synthesis in a murine erythroblastic leukemic cell: the requirement for replication to induce hemoglobin synthesis.小鼠红白血病细胞中血红蛋白合成的调控：诱导血红蛋白合成对复制的需求。
Proc Natl Acad Sci U S A. 1974 Nov;71(11):4551-5. doi: 10.1073/pnas.71.11.4551.
10
Distinction between the preneoplastic and neoplastic state of murine mammary glands.小鼠乳腺肿瘤前状态与肿瘤状态的区分。
Proc Natl Acad Sci U S A. 1972 Jun;69(6):1478-80. doi: 10.1073/pnas.69.6.1478.

利用¹⁷O核磁共振研究弗瑞德白血病细胞分化过程中的水渗透性变化。

Water permeability changes studied by 17O nuclear magnetic resonance during differentiation of Friend leukemia cells.

作者信息

Haran N, Malik Z, Lapidot A

出版信息

Proc Natl Acad Sci U S A. 1979 Jul;76(7):3363-6. doi: 10.1073/pnas.76.7.3363.

DOI:10.1073/pnas.76.7.3363
PMID:291009
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC383825/
Abstract

Water permeability of Friend leukemia cells was studied by 17O nuclear magnetic resonance during differentiation induced by dimethyl sulfoxide (Me2SO). While in noninduced cells water permeability was essentially constant during the growth period, in the Me2SO-induced cells there were two distinct periods at which the water permeability was increased by at least an order of magnitude. These periods correspond to approximately one doubling time and 6 days of growth. This change in water permeability is not due to direct interaction of Me2SO with the membrane but must be ascribed to structural changes in the membrane during the course of differentiation.

摘要

利用17O核磁共振技术研究了二甲亚砜（Me2SO）诱导分化过程中弗瑞德白血病细胞的水通透性。在未诱导的细胞中，水通透性在生长期间基本保持恒定，而在Me2SO诱导的细胞中，有两个不同的时期，水通透性至少增加了一个数量级。这些时期分别对应大约一个倍增时间和6天的生长时间。水通透性的这种变化并非由于Me2SO与细胞膜的直接相互作用，而必定归因于分化过程中细胞膜的结构变化。