Division of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, Nottingham City Hospital, Nottingham, UK.
Arthritis Research UK Centre for Sports, Exercise and Osteoarthritis, Queens Medical Centre, Nottingham, UK.
Br J Sports Med. 2018 May;52(10):678-683. doi: 10.1136/bjsports-2017-097503. Epub 2017 Nov 3.
To determine the prevalence of knee pain, radiographic knee osteoarthritis (RKOA), total knee replacement (TKR) and associated risk factors in male ex-professional footballers compared with men in the general population (comparison group).
1207 male ex-footballers and 4085 men in the general population in the UK were assessed by postal questionnaire. Current knee pain was defined as pain in or around the knees on most days of the previous month. Presence and severity of RKOA were assessed on standardised radiographs using the Nottingham Line Drawing Atlas (NLDA) in a subsample of 470 ex-footballers and 491 men in the comparison group. The adjusted risk ratio (aRR) and adjusted risk difference (aRD) with 95% CI in ex-footballers compared with the general population were calculated using the marginal model in Stata.
Ex-footballers were more likely than the comparison group to have current knee pain (aRR 1.91, 95% CI 1.77 to 2.06), RKOA (aRR 2.21, 95% CI 1.92 to 2.54) and TKR (aRR 3.61, 95% CI 2.90 to 4.50). Ex-footballers were also more likely to present with chondrocalcinosis (aRR 3.41, 95% CI 2.44 to 4.77). Prevalence of knee pain and RKOA were higher in ex-footballers at all ages. However, even after adjustment for significant knee injury and other risk factors, there was more than a doubling of risk of these outcomes in footballers.
The prevalence of all knee osteoarthritis outcomes (knee pain, RKOA and TKR) were two to three times higher in male ex-footballers compared with men in the general population group. Knee injury is the main attributable risk factor. Even after adjustment for recognised risk factors, knee osteoarthritis appear to be an occupational hazard of professional football.
确定男性前职业足球运动员与普通人群(对照组)相比,膝关节疼痛、放射学膝骨关节炎(RKOA)、全膝关节置换术(TKR)的患病率及其相关危险因素。
通过邮寄问卷评估了英国的 1207 名前足球运动员和 4085 名普通男性。当前膝关节疼痛定义为前一个月大多数日子膝关节周围疼痛。在 470 名前足球运动员和 491 名对照组男性的亚样本中,使用诺丁汉画线图谱(NLDA)标准放射影像评估 RKOA 的存在和严重程度。使用 Stata 中的边际模型计算前足球运动员与普通人群相比的调整风险比(aRR)和调整风险差异(aRD),并计算 95%置信区间。
与对照组相比,前足球运动员更有可能出现当前膝关节疼痛(aRR 1.91,95%CI 1.77 至 2.06)、RKOA(aRR 2.21,95%CI 1.92 至 2.54)和 TKR(aRR 3.61,95%CI 2.90 至 4.50)。前足球运动员也更有可能出现软骨钙质沉着症(aRR 3.41,95%CI 2.44 至 4.77)。在所有年龄段,前足球运动员膝关节疼痛和 RKOA 的患病率均较高。然而,即使在前交叉韧带损伤和其他危险因素调整后,足球运动员患这些疾病的风险仍增加了一倍以上。
与普通人群相比,男性前职业足球运动员所有膝关节骨关节炎结局(膝关节疼痛、RKOA 和 TKR)的患病率高出两到三倍。膝关节损伤是主要的归因危险因素。即使在前交叉韧带损伤和其他公认的危险因素调整后,膝关节骨关节炎似乎也是职业足球的职业危害。