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用于蛋白质化学传感的纳米结构分子印迹聚合物。

Nanostructured molecularly imprinted polymers for protein chemosensing.

机构信息

Institute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland.

Institute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland.

出版信息

Biosens Bioelectron. 2018 Apr 15;102:17-26. doi: 10.1016/j.bios.2017.10.045. Epub 2017 Oct 23.

Abstract

Molecularly imprinted polymers (MIPs) are tailor made recognition materials that can mimic biological receptors. If used as recognition units for chemosensors fabrication, they outperform natural receptors with their durability, chemical stability, and low production costs. Novel techniques of MIP deposition as thin films, surface development, and introduction of additional properties are very much demanded in terms of selective and sensitive chemosensors fabrication. Therefore, in recent years a particular attention has been paid to syntheses of nanostructured MIP films and MIP nanoparticles. The present brief review surveys novel achievements in the field of MIP nanostructures and their application for determination of protein analytes.

摘要

分子印迹聚合物(MIPs)是一种定制的识别材料,可以模拟生物受体。如果将其用作化学传感器制造的识别单元,它们将优于天然受体,具有耐用性、化学稳定性和低成本的优势。在选择性和灵敏性化学传感器制造方面,非常需要将 MIP 沉积为薄膜、表面开发和引入附加特性的新方法。因此,近年来人们特别关注合成纳米结构的 MIP 薄膜和 MIP 纳米粒子。本简要综述调查了 MIP 纳米结构领域的新成果及其在蛋白质分析物测定中的应用。

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