L'Esperance F A, Warner J W, Telfair W B, Yoder P R, Martin C A
Department of Ophthalmology, Columbia University College of Physicians and Surgeons, New York.
Arch Ophthalmol. 1989 Jan;107(1):131-9. doi: 10.1001/archopht.1989.01070010133042.
The design and development of the instrumentation utilized during the clinical and histopathologic evaluations of the first human eyes treated by argon fluoride excimer laser radiation are described. The laser, optical, alignment, measurement, and control subsystems required for this research were constructed to create a laser beam that has an axially symmetric energy distribution, can be calibrated and measured, can be aligned with the target tissue, and can be manipulated to excise surface tissue. The use of this excimer laser system has demonstrated that a nonuniform superficial lamellar keratectomy can be produced to excise areas of opacified, scarred, or abnormal cornea or to create a new anterior corneal curvature in attempts to correct refractive errors.
本文描述了在对首例接受氟化氩准分子激光辐射治疗的人眼进行临床和组织病理学评估期间所使用仪器的设计与开发。为开展此项研究而构建的激光、光学、对准、测量和控制子系统,旨在产生一束具有轴对称能量分布、可进行校准和测量、能与目标组织对准且可用于切除表层组织的激光束。该准分子激光系统的应用已表明,可进行非均匀的浅层角膜切除术,以切除角膜混浊、瘢痕化或异常区域,或尝试通过塑造新的角膜前表面曲率来矫正屈光不正。