Department of Cardiology, Onassis Cardiac Surgery Center, Sygrou 356, Kallithea 17674, Greece; Department of Pharmacy, University of Patras, Rio 26500, Greece.
Department of Chemistry, The Pennsylvania State University Brandywine, 25 Yearsley Mill Road, Media, PA 19063, USA.
Food Chem Toxicol. 2018 Jan;111:64-70. doi: 10.1016/j.fct.2017.11.002. Epub 2017 Nov 3.
A recent study identified high aldehyde emissions from e-cigarettes (ECs), that when converted to reasonable daily human EC liquid consumption, 5 g/day, gave formaldehyde exposure equivalent to 604-3257 tobacco cigarettes. We replicated this study and also tested a new-generation atomizer under verified realistic (no dry puff) conditions.
CE4v2 atomizers were tested at 3.8 V and 4.8 V, and a Nautilus Mini atomizer was tested at 9.0 W and 13.5 W. All measurements were performed in a laboratory ISO-accredited for EC aerosol collection and aldehyde measurements.
CE4v2 generated dry puffs at both voltage settings. Formaldehyde levels were >10-fold lower, acetaldehyde 6-9-fold lower and acrolein 16-26-fold lower than reported in the previous study. Nautilus Mini did not generate dry puffs, and minimal aldehydes were emitted despite >100% higher aerosol production per puff compared to CE4v2 (formaldehyde: 16.7 and 16.5 μg/g; acetaldehyde: 9.6 and 10.3 μg/g; acrolein: 8.6 and 11.7 μg/g at 9.0 W and 13.5 W, respectively). EC liquid consumption of 5 g/day reduces aldehyde exposure by 94.4-99.8% compared to smoking 20 tobacco cigarettes.
Checking for dry puffs is essential for EC emission testing. Under realistic conditions, new-generation ECs emit minimal aldehydes/g liquid at both low and high power. Validated methods should be used when analyzing EC aerosol.
最近的一项研究发现电子烟（EC）会产生大量的醛类物质，当这些醛类物质转化为合理的每日人类 EC 液体摄入量，即 5 克/天时，其甲醛暴露量相当于 604-3257 支香烟。我们复制了这项研究，并在经过验证的现实（无干吸）条件下测试了一种新一代雾化器。
在 3.8V 和 4.8V 下测试了 CE4v2 雾化器，并在 9.0W 和 13.5W 下测试了 Nautilus Mini 雾化器。所有测量均在一个经过 ISO 认证的实验室中进行，该实验室可用于收集 EC 气溶胶和测量醛类物质。
CE4v2 在两种电压设置下都会产生干吸。甲醛水平比之前的研究报告低 10 倍以上，乙醛低 6-9 倍，丙烯醛低 16-26 倍。Nautilus Mini 不会产生干吸，尽管与 CE4v2 相比，每口烟雾产生的气溶胶量高出 100%以上，但排放的醛类物质却很少（甲醛：9.0W 和 13.5W 时分别为 16.7 和 16.5μg/g；乙醛：9.6 和 10.3μg/g；丙烯醛：8.6 和 11.7μg/g）。与吸 20 支香烟相比，每天消耗 5 克 EC 液体可将醛类物质暴露量减少 94.4-99.8%。
检查是否有干吸对于 EC 排放测试至关重要。在现实条件下，新一代 EC 在低功率和高功率下每克液体的醛类排放量都很小。在分析 EC 气溶胶时应使用经过验证的方法。
