Institute of Cardiometabolism and Nutrition, ICAN, Assistance Publique Hôpitaux de Paris, Pitié-Salpêtrière Hospital, Paris, France; INSERM, UMR S U1166, Nutriomics Team, Paris, France; Sorbonne Universités, UPMC University Paris 06, UMR_S 1166 I, Nutriomics Team, Paris, France.
Eur J Intern Med. 2018 Feb;48:18-24. doi: 10.1016/j.ejim.2017.10.005. Epub 2017 Oct 27.
The composition and function of gut microbiota play a role in obesity and metabolic disease, yet the mechanisms have not been fully described. As new discoveries and advances in the field have occurred, the relevance of gut microbiota in clinical care has become more substantial. There is promising potential for manipulation of the gut microbiota as treatment of obesity and associated health complications, both as a standalone therapy and as part of interventions such as weight loss. In this review we have compiled knowledge and concepts that are important in the consideration of gut microbiota for clinical care.
肠道微生物群落的组成和功能在肥胖和代谢性疾病中发挥作用,但这些机制尚未得到充分描述。随着该领域新发现和进展的出现,肠道微生物群在临床护理中的相关性变得更加重要。作为一种单独的治疗方法,以及作为减肥等干预措施的一部分,操纵肠道微生物群作为肥胖及其相关健康并发症的治疗方法具有很大的潜力。在这篇综述中,我们汇集了在考虑肠道微生物群用于临床护理时重要的知识和概念。