阿尔塞拉菲尼γ疱疹病毒1减毒实验室菌株WC11的基因组序列。
Genome Sequence of the Alcelaphine Gammaherpesvirus 1 Attenuated Laboratory Strain WC11.
作者信息
Ensser Armin
机构信息
Virologisches Institut, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
出版信息
Genome Announc. 2017 Nov 9;5(45):e01219-17. doi: 10.1128/genomeA.01219-17.
Abstract
The complete genome sequence of the alcelaphine gammaherpesvirus 1 (AIHV-1) attenuated laboratory strain WC11 was determined from purified virion DNA. The viral light DNA (L-DNA) genome of 127,215 bp is mostly conserved compared to the pathogenic strain C500; however, 3.3 kb is deleted in two regions, affecting 4 of 10 AIHV-1-specific open reading frames.
摘要
从纯化的病毒粒子DNA中测定了羚羊γ疱疹病毒1型（AIHV-1）减毒实验室菌株WC11的完整基因组序列。与致病菌株C500相比，127,215 bp的病毒轻链DNA（L-DNA）基因组大部分是保守的；然而，在两个区域缺失了3.3 kb，影响了10个AIHV-1特异性开放阅读框中的4个。
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