FledFold：一种用于RNA二级结构预测的新型软件。
FledFold: A Novel Software for RNA Secondary Structure Prediction.
作者信息
Zhao Qi, Liu Yuanning, Duan Yunna, Dai Tao, Xu Rui, Guo Hao, Fan Daiming, Nie Yongzhan, Zhang Hao
机构信息
Computer Science and Technology Department, Jilin University, Changchun, 130000, China.
State Key Laboratory of Cancer Biology, Fourth Military Medical University, Xi'an, 710000, China.
出版信息
Lett Org Chem. 2017 Jun;14(9):714-716. doi: 10.2174/1570178614666170419122621.
BACKGROUND
RNA secondary structure is essential to understand the mechanism of RNAs.
METHOD
In this paper, fledFold, a novel software for RNA secondary structure prediction, is introduced. It combines both thermodynamic and kinetic factors of RNA secondary structures and can predict RNA secondary structures from their primary sequences with local personal computers.
RESULTS
FledFold is implemented in C++ under Windows 7 and could run on windows 7 or later version with at least 2 GB of RAM. Fledfold is user friendly and could output results with multiple formats.
CONSLUSION
FledFold will be a valuable tool for RNA researches and it could be downloaded freely from http://www.jlucomputer.com/fledfold.php.
背景
RNA二级结构对于理解RNA的机制至关重要。
方法
本文介绍了一种新型的RNA二级结构预测软件fledFold。它结合了RNA二级结构的热力学和动力学因素，并且可以在本地个人计算机上根据RNA的一级序列预测其二级结构。
结果
FledFold是在Windows 7下用C++实现的，并且可以在至少有2GB内存的Windows 7或更高版本上运行。Fledfold用户友好，可以输出多种格式的结果。
结论
FledFold将成为RNA研究的一个有价值的工具，并且可以从http://www.jlucomputer.com/fledfold.php免费下载。
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