Mao Yiran, Mu Jie, Zhao Jing, Zhao Lihui, Xin Xiaojie
Department of Ultrasound Diagnosis and Treatment , Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjins Clinical Research Centerfor Cancer , Tianjin , China.
Br J Radiol. 2018 Feb;91(1082):20170601. doi: 10.1259/bjr.20170601. Epub 2017 Nov 28.
This study is to evaluate the value of superb microvascular imaging (SMI) in assessing renal tumour vascularity and in differentiating benign from malignant renal tumours.
Patients with pathologically confirmed renal mass who underwent colour Doppler flow imaging (CDFI) and SMI examination between October 2016 and March 2017 were retrospectively analysed. Patients were classified into benign renal mass group and malignant tumour group according to their pathological results. The vascularity, vascular distribution and vessel morphology obtained from the two scanning methods were analysed and compared between the two groups.
53 patients with renal tumour were enrolled into the study, including 11 cases of benign renal tumours and 42 cases of malignant ones. SMI showed significant difference in vascularity between the two groups; CDFI showed no statistical difference. Compared with CDFI, SMI showed significantly higher grade in malignant tumour (p < 0.001), and no significant difference (p = 0.421) in benign mass. According to CDFI, there is no statistical difference in vascular distribution and vessel morphology (p = 0.432, p = 0.122) between the two groups, while SMI method showed significant difference (p < 0.05) between the two groups. SMI was significantly more sensitive and accurate than CDFI.
Comparing with CDFI, SMI could effectively detect vascularity, vascular characteristics and distribution and annular blood flow in renal tumour. SMI appears more sensitive and precise in distinguishing benign renal mass from malignant tumour. Advances in knowledge: SMI seems potentially valuable in evaluating renal tumour vascularity and in differentiating benign from malignant renal tumours.
本研究旨在评估超微血管成像（SMI）在评估肾肿瘤血管情况以及鉴别肾良性肿瘤与恶性肿瘤方面的价值。
回顾性分析2016年10月至2017年3月期间接受彩色多普勒血流成像（CDFI）和SMI检查且病理确诊为肾肿物的患者。根据病理结果将患者分为肾良性肿物组和恶性肿瘤组。分析并比较两组通过两种扫描方法获得的血管情况、血管分布及血管形态。
53例肾肿瘤患者纳入研究，其中良性肾肿瘤11例，恶性肾肿瘤42例。SMI显示两组在血管情况上有显著差异；CDFI显示无统计学差异。与CDFI相比，SMI在恶性肿瘤中的分级显著更高（p < 0.001），在良性肿物中无显著差异（p = 0.421）。根据CDFI，两组在血管分布及血管形态上无统计学差异（p = 0.432，p = 0.122），而SMI方法显示两组间有显著差异（p < 0.05）。SMI比CDFI显著更敏感且准确。
与CDFI相比，SMI能有效检测肾肿瘤的血管情况、血管特征及分布以及环状血流。SMI在鉴别肾良性肿物与恶性肿瘤方面似乎更敏感且精确。知识进展：SMI在评估肾肿瘤血管情况及鉴别肾良性肿瘤与恶性肿瘤方面似乎具有潜在价值。
