Arthropod-Borne Animal Diseases Research Unit, Center for Grain and Animal Health Research, Agricultural Research Service, USDA, Manhattan, KS, United States.
Arthropod-Borne Animal Diseases Research Unit, Center for Grain and Animal Health Research, Agricultural Research Service, USDA, Manhattan, KS, United States.
Curr Opin Virol. 2017 Dec;27:36-41. doi: 10.1016/j.coviro.2017.10.007. Epub 2017 Nov 10.
A comparison of two geographicallly distinct viruses in the order Bunyavirales that are zoonotic and known to cause congenital abnormalities in ruminant livestock was performed. One of these viruses, Cache Valley fever virus, is found in the Americas and is primarily associated with disease in sheep. The other, Rift Valley fever virus, is found in Sub-Saharan Africa and is associated with disease in camels, cattle, goats and sheep. Neither virus has been associated with teratogenicity in humans to date. These two viruses are briefly reviewed and potential for genetic changes especially if introduced into new ecology that could affect pathogenicity are discussed.
对两种在布尼亚病毒目下的具有地理差异的、已知会导致反刍家畜先天畸形的人畜共患病病毒进行了比较。其中一种病毒是卡什峡谷热病毒，它存在于美洲，主要与绵羊疾病有关。另一种是裂谷热病毒，它存在于撒哈拉以南非洲，与骆驼、牛、山羊和绵羊的疾病有关。到目前为止，这两种病毒都与人类的致畸性无关。本文简要回顾了这两种病毒，并讨论了它们发生遗传变化的可能性，特别是如果引入新的生态环境，可能会影响其致病性。
