Internal Medicine Department B, General Hospital of Heraklion Venizeleio-Pananeio, Leoforos Knossou, 71409, Heraklion, Greece.
General Medicine, University Hospital of Heraklion, Heraklion, Greece.
Infection. 2018 Jun;46(3):293-301. doi: 10.1007/s15010-017-1100-6. Epub 2017 Nov 11.
There is little guidance regarding the evaluation and management of patients with Staphylococcus aureus bacteriuria (SABU). Here, we aimed to provide an up-to-date review of the literature.
We searched PubMed, Scopus, and clinical trial registries for articles evaluating the epidemiology of SABU, risk factors of SABU, the association of SABU with urinary tract infection, bacteremia and invasive S. aureus infections, and the management of patients with SABU.
S. aureus is an uncommon isolate in urine cultures. It is more common among certain patients, e.g., patients with indwelling urinary tract devices or prior urinary tract instrumentation. SABU may represent asymptomatic bacteriuria, primary urinary tract infection, or hematogenous seeding of the urinary tract associated with other foci of infection. SABU may also serve as the focus for subsequent bacteremia and invasive infections. We did not find any clinical trials regarding the management of patients with SABU.
Based on our review, we suggest an algorithmic approach for the evaluation and management of patients with SABU. However, evidence from clinical trials is lacking and there are several gaps in the current literature. These are discussed in this review.
对于金黄色葡萄球菌菌尿症（SABU）患者的评估和管理，目前几乎没有指导。在这里，我们旨在提供最新的文献综述。
我们在 PubMed、Scopus 和临床试验登记处搜索了评估 SABU 的流行病学、SABU 的危险因素、SABU 与尿路感染、菌血症和侵袭性金黄色葡萄球菌感染的关联以及 SABU 患者管理的文章。
金黄色葡萄球菌在尿液培养物中是一种不常见的分离株。它在某些患者中更为常见，例如留置导尿管或先前尿路器械的患者。SABU 可能代表无症状菌尿、原发性尿路感染或与其他感染灶相关的血源性尿路播散。SABU 也可能成为随后菌血症和侵袭性感染的病灶。我们没有发现任何关于 SABU 患者管理的临床试验。
根据我们的综述，我们建议对 SABU 患者进行评估和管理的算法方法。然而，目前缺乏临床试验证据，并且当前文献中存在几个空白。在这篇综述中讨论了这些问题。
