马鞭草酮，一种源自夏威夷植物相关真菌FT431的八氢-5H-色烯-5-酮。
Verbenanone, an octahydro-5H-chromen-5-one from a Hawaiian-Plant Associated Fungus FT431.
作者信息
Li Chunshun, Sarotti Ariel M, Turkson James, Cao Shugeng
机构信息
Department of Pharmaceutical Sciences, Daniel K. Inouye College of Pharmacy, University of Hawaii at Hilo, 200 West Kawili Street, Hilo, Hawai'i 96720, United States.
Cancer Biology, University of Hawaii Cancer Center, 701 Ilalo Street, Honolulu, Hawai'i 96813, United States.
出版信息
Tetrahedron Lett. 2017 Jun 7;58(23):2290-2293. doi: 10.1016/j.tetlet.2017.04.096. Epub 2017 May 2.
Abstract
A new secondary metabolite verbenanone () with a unique (4a,8a)-octahydro-5H-chromen-5-one moiety has been obtained from the endophytic fungus FT431, which was isolated from the native Hawaiian plant sp. The structure of compound was characterized based on NMR and MS spectroscopic analysis. The absolute configuration (AC) of compound was determined by Mosher acids. Compound was tested against A2780 and A2780cisR, but it was inactive.
摘要
一种具有独特的(4a,8a)-八氢-5H-色烯-5-酮部分的新的次生代谢产物马鞭草烯酮()已从内生真菌FT431中获得，该真菌是从夏威夷本土植物 sp.中分离得到的。化合物 的结构通过核磁共振和质谱光谱分析进行了表征。化合物 的绝对构型通过莫舍尔酸确定。化合物 针对A2780和A2780cisR进行了测试，但没有活性。
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