Hyde F W, Johnson R C, White T J, Shelburne C E
Biosciences Laboratory, 3M Center, St. Paul, Minnesota 55144-1000.
J Clin Microbiol. 1989 Jan;27(1):58-61. doi: 10.1128/jcm.27.1.58-61.1989.
Lyme disease is a seasonal tick-borne malady which has worldwide distribution. Early and accurate diagnosis of Lyme disease is essential for successful antibiotic therapy. Symptoms are too vague to make an early diagnosis based on conventional criteria. We report the detection of antigens of Borrelia burgdorferi, causative agent of Lyme disease, in the urine of infected mice and humans. This technique may eventually provide a rapid diagnostic test for the early and accurate detection of this illness.
莱姆病是一种由蜱传播的季节性疾病，在全球范围内均有分布。莱姆病的早期准确诊断对于抗生素治疗的成功至关重要。其症状过于模糊，难以依据传统标准进行早期诊断。我们报告了在受感染小鼠和人类尿液中检测到莱姆病病原体伯氏疏螺旋体的抗原。这项技术最终可能会提供一种用于早期准确检测该疾病的快速诊断测试。
